Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges.
TLDR
Among patients with pneumonia caused by SARS-CoV-2 (novel coronavirus pneumonia or Wuhan pneumonia), fever was the most common symptom, followed by cough, and bilateral lung involvement with ground-glass opacity was themost common finding from computed tomography images of the chest.Citations
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Safe and effective management of tracheostomy in COVID-19 patients.
TL;DR: This work explored the safe and effective management of tracheostomy in COVID‐19 patients, to benefit patients and protect health care workers at the same time.
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Changes in substance use among young adults during a respiratory disease pandemic
TL;DR: Self-reported substance use among young adults was observed to change during a pandemic, and the degree of loneliness appears to impact these changes.
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COVID-19 is more severe in patients with hypertension; ACEI/ARB treatment does not influence clinical severity and outcome.
Jianhua Hu,Xiaoli Zhang,Xuan Zhang,Hong Zhao,Jiangshan Lian,Shaorui Hao,Hongyu Jia,Meifang Yang,Yingfeng Lu,Dairong Xiang,Huan Cai,Shanyan Zhang,Jueqing Gu,Chanyuan Ye,Guodong Yu,Ciliang Jin,Lin Zheng,Yida Yang,Jifang Sheng +18 more
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SARS-CoV-2 and the possible connection to ERs, ACE2, and RAGE: Focus on susceptibility factors.
Roberta Sessa Stilhano,Angelica Jardim Costa,Michelle Sayuri Nishino,Shahin Shams,Cynthia Silva Bartolomeo,Ana Cristina Breithaupt-Faloppa,Eduardo A. Silva,Ana Lopez Ramirez,Carla Máximo Prado,Rodrigo Portes Ureshino +9 more
TL;DR: The current state of the field regarding SARS‐CoV‐2 research is presented and where research is needed is illuminated to better define the role both estrogen and metabolic comorbidities have in the COVID‐19 disease state, which can be key in screening potential therapeutic options as the search for effective treatments continue.
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What could explain the late emergence of COVID-19 in Africa?
Rym Lalaoui,Sofiane Bakour,Didier Raoult,Pierre Verger,Cheikh Sokhna,Christian Devaux,Christian Devaux,Bruno Pradines,Jean-Marc Rolain +8 more
TL;DR: Several hypotheses are being discussed, including the lack of health care infrastructure capable of clinically detecting and confirming COVID-19 cases, the implementation of social distancing and hygiene, international air traffic flows, the climate, the relatively young and rural population, and the genetic polymorphism of the ACE2 receptor.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
Journal ArticleDOI
A Novel Coronavirus from Patients with Pneumonia in China, 2019.
Na Zhu,Dingyu Zhang,Wenling Wang,Xingwang Li,Bo Yang,Jingdong Song,Xiang Zhao,Baoying Huang,Weifeng Shi,Roujian Lu,Peihua Niu,Faxian Zhan,Xuejun Ma,Dayan Wang,Wenbo Xu,Wenbo Xu,Guizhen Wu,George F. Gao,Wenjie Tan +18 more
TL;DR: Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily, which is the seventh member of the family of coronaviruses that infect humans.
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A pneumonia outbreak associated with a new coronavirus of probable bat origin
Peng Zhou,Xing-Lou Yang,Xian Guang Wang,Ben Hu,Lei Zhang,Wei Zhang,Hao Rui Si,Yan Zhu,Bei Li,Chao Lin Huang,Hui-Dong Chen,Jing Chen,Yun Luo,Hua Guo,Ren Di Jiang,Meiqin Liu,Ying Chen,Xu Rui Shen,Xi Wang,Xiao Shuang Zheng,Kai Zhao,Quanjiao Chen,Fei Deng,Lin Lin Liu,Bing Yan,Fa Xian Zhan,Yan-Yi Wang,Gengfu Xiao,Zhengli Shi +28 more
TL;DR: Identification and characterization of a new coronavirus (2019-nCoV), which caused an epidemic of acute respiratory syndrome in humans in Wuhan, China, and it is shown that this virus belongs to the species of SARSr-CoV, indicates that the virus is related to a bat coronav virus.
Journal ArticleDOI
Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
Dawei Wang,Bo Hu,Chang Hu,Fangfang Zhu,Xing Liu,Jing Zhang,Binbin Wang,Hui Xiang,Zhenshun Cheng,Yong Xiong,Yan Zhao,Yirong Li,Xinghuan Wang,Zhiyong Peng +13 more
TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
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Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
TL;DR: Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection.
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
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