Journal ArticleDOI
Sex differences in exercise efficacy to improve cognition: A systematic review and meta-analysis of randomized controlled trials in older humans
TLDR
It is suggested that women's executive processes may benefit more from exercise than men, and aerobic training led to greater benefits than resistance training in global cognitive function and executive functions, while multimodal combinedTraining led togreat benefits than aerobic training for global Cognitive function, episodic memory, and word fluency.About:
This article is published in Frontiers in Neuroendocrinology.The article was published on 2017-07-01. It has received 247 citations till now. The article focuses on the topics: Aerobic exercise & Executive functions.read more
Citations
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Journal ArticleDOI
The Impact of Different Types of Exercise Training on Peripheral Blood Brain-Derived Neurotrophic Factor Concentrations in Older Adults: A Meta-Analysis
TL;DR: To increase the peripheral blood BDNF concentrations in older adults, strength training and combined aerobic/strength training is effective and more studies are needed to examine the impact of aerobic exercise training.
Journal ArticleDOI
Sex differences in aerobic exercise efficacy to improve cognition: A systematic review and meta-analysis of studies in older rodents.
TL;DR: Results indicate that compared to controls, AT improved hippocampus-dependent and -independent learning and memory and increased brain-derived neurotrophic factor compared to Controls, with larger effects in females.
Journal ArticleDOI
Sex Difference in Aerobic Exercise Efficacy to Improve Cognition in Older Adults with Vascular Cognitive Impairment: Secondary Analysis of a Randomized Controlled Trial.
Cindy K. Barha,Ging-Yuek Robin Hsiung,Ging-Yuek Robin Hsiung,John R. Best,Jennifer C. Davis,Janice J. Eng,Claudia Jacova,Claudia Jacova,Philip E. Lee,Michelle Munkacsy,Winnie Cheung,Teresa Liu-Ambrose +11 more
TL;DR: Evidence is provided that sex differences exist in AT efficacy on brain health as well as in the biological mechanisms subserving AT, which led to significant gains in functional fitness capacity in males only.
Journal ArticleDOI
Biological Sex: A Potential Moderator of Physical Activity Efficacy on Brain Health.
Cindy K. Barha,Cindy K. Barha,C. Hsu,C. Hsu,Lisanne F. ten Brinke,Lisanne F. ten Brinke,Teresa Liu-Ambrose,Teresa Liu-Ambrose +7 more
TL;DR: The argument that biological sex is a potent moderator of the relationship between physical activity and brain health in older adults is presented and highlights some of the potential neurobiological mechanisms underlying this sex difference.
Journal ArticleDOI
Sex differences in Alzheimer's disease: Understanding the molecular impact.
TL;DR: The latest and most relevant literature is reviewed, highlighting the importance of understanding sex dimorphism from a molecular perspective and its association to clinical trial design and development in AD research field.
References
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Journal ArticleDOI
The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration
Alessandro Liberati,Douglas G. Altman,Jennifer Tetzlaff,Cynthia D. Mulrow,Peter C Gøtzsche,John P. A. Ioannidis,Mike Clarke,Mike Clarke,Philip J. Devereaux,Jos Kleijnen,David Moher +10 more
TL;DR: An Explanation and Elaboration of the PRISMA Statement is presented and updated guidelines for the reporting of systematic reviews and meta-analyses are presented.
Journal ArticleDOI
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration
Alessandro Liberati,Douglas G. Altman,Jennifer Tetzlaff,Cynthia D. Mulrow,Peter C Gøtzsche,John P. A. Ioannidis,Mike Clarke,Mike Clarke,Philip J. Devereaux,Jos Kleijnen,David Moher +10 more
TL;DR: This Explanation and Elaboration document explains the meaning and rationale for each checklist item and includes an example of good reporting and, where possible, references to relevant empirical studies and methodological literature.
Journal ArticleDOI
CONSORT 2010 Explanation and Elaboration: updated guidelines for reporting parallel group randomised trials
David Moher,Sally Hopewell,Kenneth F. Schulz,Victor M. Montori,Peter C Gøtzsche,Philip J. Devereaux,Diana Elbourne,Matthias Egger,Douglas G. Altman +8 more
TL;DR: This update of the CONSORT statement improves the wording and clarity of the previous checklist and incorporates recommendations related to topics that have only recently received recognition, such as selective outcome reporting bias.
Journal ArticleDOI
Exercise training increases size of hippocampus and improves memory
Kirk I. Erickson,Michelle W. Voss,Ruchika Shaurya Prakash,Chandramallika Basak,Amanda N. Szabo,Laura Chaddock,Jennifer S. Kim,Susie Heo,Heloisa Alves,Siobhan M. White,Thomas R. Wójcicki,Emily L. Mailey,Victoria J. Vieira,Stephen A. Martin,Brandt D. Pence,Jeffrey A. Woods,Edward McAuley,Arthur F. Kramer +17 more
TL;DR: It is shown that aerobic exercise training increases the size of the anterior hippocampus, leading to improvements in spatial memory, and that increased hippocampal volume is associated with greater serum levels of BDNF, a mediator of neurogenesis in the dentate gyrus.
Journal ArticleDOI
Fitness Effects on the Cognitive Function of Older Adults: A Meta-Analytic Study
TL;DR: Fitness training was found to have robust but selective benefits for cognition, with the largest fitness-induced benefits occurring for executive-control processes.
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Fitness Effects on the Cognitive Function of Older Adults: A Meta-Analytic Study
Exercise training increases size of hippocampus and improves memory
Kirk I. Erickson,Michelle W. Voss,Ruchika Shaurya Prakash,Chandramallika Basak,Amanda N. Szabo,Laura Chaddock,Jennifer S. Kim,Susie Heo,Heloisa Alves,Siobhan M. White,Thomas R. Wójcicki,Emily L. Mailey,Victoria J. Vieira,Stephen A. Martin,Brandt D. Pence,Jeffrey A. Woods,Edward McAuley,Arthur F. Kramer +17 more