Journal ArticleDOI
Structural Basis of a Fungal Galectin from Agrocybe cylindracea for Recognizing Sialoconjugate
TLDR
The refined structure shows that ACG is a "proto"-type galectin composed of a beta-sandwich of two antiparallel sheets, each with six strands, in contrast to the five and six strands in animal galectins, which is among the "layer"-type.About:
This article is published in Journal of Molecular Biology.The article was published on 2005-08-26. It has received 52 citations till now. The article focuses on the topics: Galectin.read more
Citations
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Journal ArticleDOI
Sialic acid-specific lectins: occurrence, specificity and function.
TL;DR: This review will present a detailed overview of the current knowledge regarding the occurrence, specificity and function of sialic acid-specific lectins, particularly those that occur in viruses, bacteria and non-vertebrate eukaryotes.
Journal ArticleDOI
Mushroom Lectins: Specificity, Structure and Bioactivity Relevant to Human Disease
TL;DR: This review provides an up-to-date summary on the biochemical, molecular and structural properties of mushroom lectins, as well as their versatile applications specifically focusing on mushroom lectin bioactivity.
Journal ArticleDOI
Diversified carbohydrate-binding lectins from marine resources.
TL;DR: This work reviews the multiple lectins from marine resources including fishes and sea invertebrate in terms of their structure-activity relationships and molecular evolution, and focuses on the unique structural properties and Molecular evolution of C-type lectins, galectin, F- type lectin, and rhamnose-binding lectin families.
Journal ArticleDOI
Mutational Tuning of Galectin-3 Specificity and Biological Function
Emma Salomonsson,Michael C. Carlsson,Veronica Osla,Ruth Hendus-Altenburger,Barbro Kahl-Knutson,Christopher T. Öberg,Anders Sundin,Rickard Nilsson,Eva Nordberg-Karlsson,Ulf J. Nilsson,Anna Karlsson,James M. Rini,Hakon Leffler +12 more
TL;DR: Ten mutants of human galectin-3 are produced, with changes in these adjacent sites that have altered carbohydrate-binding fine specificity but that retain the basic β-galactoside binding activity, and help to define the differences in fine specificity shown by Xenopus, mouse, and human galector-3 and, as such, the evidence for adaptive change during evolution.
Journal ArticleDOI
β-propeller crystal structure of Psathyrella velutina lectin : An integrin-like fungal protein interacting with monosaccharides and calcium
Gianluca Cioci,Edward P. Mitchell,Valerie Chazalet,Henri Debray,Stefan Oscarson,Martina Lahmann,Catherine Gautier,Christelle Breton,Serge Pérez,Anne Imberty +9 more
TL;DR: The multispecificity and high multivalency of this mushroom lectin, combined with its similarity to the extracellular domain of an important class of cell adhesion molecules, integrins, are another example of the outstanding success of beta-propeller structures as molecular binding machines in nature.
References
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Clustal w: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
TL;DR: The sensitivity of the commonly used progressive multiple sequence alignment method has been greatly improved and modifications are incorporated into a new program, CLUSTAL W, which is freely available.
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PROCHECK: a program to check the stereochemical quality of protein structures
TL;DR: The PROCHECK suite of programs as mentioned in this paper provides a detailed check on the stereochemistry of a protein structure and provides an assessment of the overall quality of the structure as compared with well refined structures of the same resolution.
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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination
Axel T. Brunger,Axel T. Brunger,Paul D. Adams,G M Clore,W. L. DeLano,Piet Gros,R.W. Grosse-Kunstleve,R.W. Grosse-Kunstleve,Jiansheng Jiang,J. Kuszewski,Michael Nilges,Navraj S. Pannu,Randy J. Read,Luke M. Rice,Thomas Simonson,Gregory L. Warren +15 more
TL;DR: The Crystallography & NMR System (CNS) as mentioned in this paper is a software suite for macromolecular structure determination by X-ray crystallography or solution nuclear magnetic resonance (NMR) spectroscopy.
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Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features
Wolfgang Kabsch,Chris Sander +1 more
TL;DR: A set of simple and physically motivated criteria for secondary structure, programmed as a pattern‐recognition process of hydrogen‐bonded and geometrical features extracted from x‐ray coordinates is developed.
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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures
TL;DR: The MOLSCRIPT program as discussed by the authors produces plots of protein structures using several different kinds of representations, including simple wire models, ball-and-stick models, CPK models and text labels.