Journal ArticleDOI
Suzuki–Miyaura cross coupling reaction: recent advancements in catalysis and organic synthesis
Reads0
Chats0
TLDR
The advancements (within the last 4 years) in catalysis related to SMCR that would be beneficial for researchers in designing synthetic protocols for the preparation of pharmacophores as well as drug molecules are discussed.About:
This article is published in Catalysis Science & Technology.The article was published on 2021-03-02. It has received 68 citations till now. The article focuses on the topics: Organic synthesis.read more
Citations
More filters
Journal Article
Reaction Scope and Mechanistic Insights of Nickel-Catalyzed Migratory Suzuki-Miyaura Cross-Coupling
TL;DR: A nickel-catalyzed migratory Suzuki–Miyaura cross-coupling featuring high benzylic or allylic selectivity and unactivated alkyl electrophiles and aryl or vinyl boronic acids can be efficiently transferred to diarylalkane or allylbenzene derivatives under mild conditions.
Journal ArticleDOI
Mechanochemistry: New Tools to Navigate the Uncharted Territory of “Impossible” Reactions
Federico Cuccu,Lidia De Luca,Francesco Delogu,Evelina Colacino,Niclas Solin,Rita Mocci,Andrea Porcheddu +6 more
TL;DR: In this paper , the reader is introduced to an intriguing research subject not yet fully explored and waiting for improved understanding, namely, organic transformations that, although impossible in solution, become possible under mechanochemical processing conditions, simultaneously entailing innovation and expanding the chemical space.
Journal ArticleDOI
The emergence of the C–H functionalization strategy in medicinal chemistry and drug discovery
TL;DR: In this paper, the authors discuss the recent trends of C-H activation methodologies such as synthesis of medicinal scaffolds through a cascade of cascade-based activation and activation/annulation cascade, arylation for sp2sp2 and sp2-sp3 cross-coupling, borylation/silylation to introduce a functional linchpin for further manipulation, amination for N-heterocycles and hydrogen bond acceptors, C-h fluorination/fluoroalkylation to tune polarity and lipophilicity, peptide modification and
Journal ArticleDOI
Stabilization of ruthenium on biochar-nickel magnetic nanoparticles as a heterogeneous, practical, selective, and reusable nanocatalyst for the Suzuki C–C coupling reaction in water
Parisa Moradi,Maryam Hajjami +1 more
TL;DR: In this article , Ru-dithizone@biochar-Ni MNPs were modified by dithizones ligand and then applied for the fabrication of a ruthenium catalyst.
Nickel-Catalyzed Carbon–Carbon Bond-Forming Reactions of Unactivated Tertiary Alkyl Halides: Suzuki Arylations
TL;DR: This approach to the synthesis of all-carbon quaternary carbon centers does not suffer from isomerization of the alkyl group, in contrast with the umpolung strategy for this bond construction.
References
More filters
Journal ArticleDOI
Polydopamine supported palladium nanoparticles: Highly efficient catalysts in Suzuki cross-coupling and tandem Suzuki cross-coupling/nitroarene reductions under green reaction conditions
TL;DR: In this article, the application of an easily prepared and highly active polydopamine-supported Pd nanoparticles catalyst in Suzuki crosscouplings and tandem Suzuki cross-coupling/catalytic transfer hydrogenation sequences under green reaction conditions is described.
Journal ArticleDOI
Recyclable and Reusable Heteroleptic Nickel Catalyst Immobilized on Metal–Organic Framework for Suzuki–Miyaura Coupling
Palani Elumalai,Hind Mamlouk,Wubulikasimu Yiming,Liang Feng,Shuai Yuan,Hong-Cai Zhou,Sherzod T. Madrahimov +6 more
TL;DR: A recyclable and highly active nickel catalyst immobilized on MOF for Suzuki-Miyaura coupling reaction, which operates under mild conditions and gave good to excellent isolated yields with a range of functionalities, including heterocycles on aryl bromide with widely varying electronic properties.
Journal ArticleDOI
Pd nanoparticle and molecular Pd2+ leaching pathways for a strongly acid versus strongly basic resin supported Pd nanoparticle catalyst in Suzuki coupling
TL;DR: In this article, the Suzuki reaction between iodobenzene and phenylboronic acid with K2CO3 as base in 1:1 (v/v) DMF/H2O at 40°C was investigated.
Journal ArticleDOI
Nickel(II) Nanoparticles Immobilized on EDTA-Modified Fe3O4@SiO2 Nanospheres as Efficient and Recyclable Catalysts for Ligand-Free Suzuki–Miyaura Coupling of Aryl Carbamates and Sulfamates
TL;DR: Using the mentioned heterogeneous nanocatalyst in such reactions generated corresponding products in good to excellent yields in which the catalyst could easily be recovered from the reaction mixture with an external magnetic field to reuse directly for the next several cycles without significant loss of its activity.
Journal ArticleDOI
Microwave-assisted aqueous carbon–carbon cross-coupling reactions of aryl chlorides catalysed by reduced graphene oxide supported palladium nanoparticles
TL;DR: In this article, a simple and green in situ assembly and reduction approach was developed for the fabrication of reduced graphene oxide supported palladium nanoparticles (Pd/rGO), which were uniformly dispersed on the sheets of rGO with an average size of around 2.0 nm.
Related Papers (5)
The B‐Alkyl Suzuki—Miyaura Cross‐Coupling Reaction: Development, Mechanistic Study, and Applications in Natural Product Synthesis
Oxygen-Promoted Suzuki-Miyaura Reaction for Efficient Construction of Biaryls
Palladium-Catalyzed Suzuki-Miyaura Cross-coupling Reactions Employing Dialkylbiaryl Phosphine Ligands
Ruben Martin,Stephen L. Buchwald +1 more