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Open AccessJournal ArticleDOI

Taverna: a tool for building and running workflows of services

TLDR
Taverna is an application that eases the use and integration of the growing number of molecular biology tools and databases available on the web, especially web services, to perform a range of different analyses, such as sequence analysis and genome annotation.
Abstract
Taverna is an application that eases the use and integration of the growing number of molecular biology tools and databases available on the web, especially web services. It allows bioinformaticians to construct workflows or pipelines of services to perform a range of different analyses, such as sequence analysis and genome annotation. These high-level workflows can integrate many different resources into a single analysis. Taverna is available freely under the terms of the GNU Lesser General Public License (LGPL) from http://taverna.sourceforge.net/.

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Unipro UGENE

TL;DR: Unipro UGENE integrates widely used bioinformatics tools within a common user interface and provides visualization modules for biological objects such as annotated genome sequences, Next Generation Sequencing (NGS) assembly data, multiple sequence alignments, phylogenetic trees and 3D structures.
Journal ArticleDOI

A new bioinformatics analysis tools framework at EMBL–EBI

TL;DR: A new framework aimed at both novice as well as expert users that exposes novel methods of obtaining annotations and visualizing sequence analysis results through one uniform and consistent interface is presented.
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Analysis Tool Web Services from the EMBL-EBI

TL;DR: Since 2004 the European Bioinformatics Institute (EMBL-EBI) has provided access to a wide range of databases and analysis tools via Web Services interfaces, which allow their integration into other tools, applications, web sites, pipeline processes and analytical workflows.
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The Arabidopsis Information Resource (TAIR): gene structure and function annotation.

TL;DR: A combination of manual and computational methods were used to generate this release, which contains 27 029 protein-coding genes, 3889 pseudogenes or transposable elements and 1123 ncRNAs (32 041 genes in all, 37 019 gene models).
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DIANA-microT web server v5.0: service integration into miRNA functional analysis workflows

TL;DR: DIANA-microT v5.0, the new version of the microT server, has been significantly enhanced with an improved target prediction algorithm, DIANA- microT-CDS, which has been updated to incorporate miRBase version 18 and Ensembl version 69.
References
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Journal ArticleDOI

Database resources of the National Center for Biotechnology Information

TL;DR: In addition to maintaining the GenBank(R) nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides data analysis and retrieval resources for the data in GenBank and other biological data made available through NCBI’s website.
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R: A Language for Data Analysis and Graphics

TL;DR: In this article, the authors discuss their experience designing and implementing a statistical computing language, which combines what they felt were useful features from two existing computer languages, and they feel that the new language provides advantages in the areas of portability, computational efficiency, memory management, and scope.
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Prediction of Complete Gene Structures in Human Genomic DNA

TL;DR: A general probabilistic model of the gene structure of human genomic sequences which incorporates descriptions of the basic transcriptional, translational and splicing signals, as well as length distributions and compositional features of exons, introns and intergenic regions is introduced.
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From genomics to chemical genomics: new developments in KEGG

TL;DR: The scope of KEGG LIGAND has been significantly expanded to cover both endogenous and exogenous molecules, and RPAIR contains curated chemical structure transformation patterns extracted from known enzymatic reactions, which would enable analysis of genome-environment interactions.
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Pfam: clans, web tools and services

TL;DR: Improvements to the range of Pfam web tools and the first set of PfAm web services that allow programmatic access to the database and associated tools are presented.
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