Journal ArticleDOI
The race for coronavirus vaccines: a graphical guide.
TLDR
Eight ways in which scientists hope to provide immunity to SARS-CoV-2 .Citations
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Journal ArticleDOI
Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes
Tongqing Zhou,I-Ting Teng,Adam S. Olia,Gabriele Cerutti,Jason Gorman,Alexandra Nazzari,Wei Shi,Yaroslav Tsybovsky,Lingshu Wang,Shuishu Wang,Baoshan Zhang,Yi Zhang,Phinikoula S. Katsamba,Yuliya Petrova,Bailey B. Banach,Ahmed S. Fahad,Lihong Liu,Sheila N. Lopez Acevedo,Bharat Madan,Matheus Oliveira de Souza,Xiaoli Pan,Pengfei Wang,Jacy R. Wolfe,Michael T. Yin,David D. Ho,Emily Phung,Anthony T. DiPiazza,Lauren A. Chang,Olubukola M. Abiona,Kizzmekia S. Corbett,Brandon J. DeKosky,Barney S. Graham,John R. Mascola,John Misasi,Tracy J. Ruckwardt,Nancy J. Sullivan,Lawrence Shapiro,Lawrence Shapiro,Peter D. Kwong,Peter D. Kwong +39 more
TL;DR: In this article, the SARS-CoV-2 spike ectodomain was characterized for antigenicity and ACE2 recognition, and the structure of the probe was determined by cryo-electron microscopy.
Journal ArticleDOI
A Retrospective Analysis of Social Media posts pertaining to COVID-19 vaccination side effects
Max-Philipp Lentzen,Viola Huebenthal,Rolf Kaiser,Matthias Kreppel,Joachim E. Zoeller,Matthias Zirk +5 more
TL;DR: In this paper, the authors present an analysis of quantity and quality of social media content according to COVID-19 vaccinations and its side effects and evaluate its educational quality by three examiners of different educational levels.
Journal ArticleDOI
A retrospective analysis of social media posts pertaining to COVID-19 vaccination side effects
TL;DR: In this paper , the authors present an analysis of quantity and quality of social media content according to COVID-19 vaccinations and its side effects and evaluate its educational quality by three examiners of different educational levels.
Posted ContentDOI
SARS-CoV-2 infected cells present HLA-I peptides from canonical and out-of-frame ORFs
Shira Weingarten-Gabbay,Shira Weingarten-Gabbay,Susan Klaeger,Siranush Sarkizova,Leah R. Pearlman,Da-Yuan Chen,Matthew R. Bauer,Matthew R. Bauer,Hannah B. Taylor,Hasahn L. Conway,Christopher Tomkins-Tinch,Christopher Tomkins-Tinch,Yaara Finkel,Aharon Nachshon,Matteo Gentili,Keith Rivera,Derin B. Keskin,Charles M. Rice,Karl R. Clauser,Nir Hacohen,Nir Hacohen,Steven A. Carr,Jennifer G. Abelin,Mohsan Saeed,Pardis C. Sabeti +24 more
TL;DR: The first HLA-I immunopeptidome of SARS-CoV-2 is reported in two human cell lines at different times post-infection using mass spectrometry and it is estimated that a pool of 24 peptides would provide one or more peptides for presentation by at least one HLA allele in 99% of the human population.
Journal ArticleDOI
The mutational landscape of SARS-CoV-2 variants diversifies T cell targets in an HLA-supertype-dependent manner
TL;DR: This article analyzed a total of 330,246 high-quality SARS-CoV-2 genome assemblies, sampled across 143 countries and all major continents from December 2019 to December 2020 before mass vaccination or the rise of the Delta variant.
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