Journal ArticleDOI
The race for coronavirus vaccines: a graphical guide.
TLDR
Eight ways in which scientists hope to provide immunity to SARS-CoV-2 .Citations
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Journal ArticleDOI
COVID-19 vaccines and treatments nationalism: Challenges for low-income countries and the attainment of the SDGs.
TL;DR: The paper recommends the continued mobilisation by the World Health Organisation and other key stakeholders in supporting the GAVI vaccine alliance and the Coalition for Epidemic Preparedness Innovations (COVAX) global vaccines initiative that seeks to make two billion vaccine doses available to 92 low and middle-income countries by December 2021.
Journal ArticleDOI
COVID-19 Vaccines: "Warp Speed" Needs Mind Melds, Not Warped Minds.
John P. Moore,Per Johan Klasse +1 more
TL;DR: The immunogenicity of leading vaccine candidates tested to date in animals and humans is summarized, which range from the hoped-for rapid success to a catastrophic adverse influence on vaccine uptake generally.
Journal ArticleDOI
COVID-19: Mechanisms of Vaccination and Immunity.
TL;DR: The pros and cons of available vaccine platforms and options to accelerate vaccine development towards the safe immunization of the world’s population against SARS-CoV-2 are reviewed.
Journal ArticleDOI
Future antiviral surfaces: Lessons from COVID-19 pandemic
TL;DR: This work maps possible solutions to inactivate the receptors of the coronavirus spikes and resist the transmission of the COVID-19 and other infectious diseases, and contribute to the prevention of future outbreaks and control of epidemics.
Journal ArticleDOI
Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs.
Shira Weingarten-Gabbay,Shira Weingarten-Gabbay,Susan Klaeger,Siranush Sarkizova,Leah R. Pearlman,Da Yuan Chen,Kathleen Gallagher,Matthew R. Bauer,Matthew R. Bauer,Hannah B. Taylor,W. Augustine Dunn,Christina Tarr,John Sidney,Suzanna Rachimi,Hasahn L. Conway,Katelin Katsis,Yuntong Wang,Del Leistritz-Edwards,Melissa R. Durkin,Christopher Tomkins-Tinch,Christopher Tomkins-Tinch,Yaara Finkel,Aharon Nachshon,Matteo Gentili,Keith Rivera,Isabel P. Carulli,Vipheaviny Chea,Abishek Chandrashekar,Cansu Cimen Bozkus,Mary Carrington,Kendall M. Lavin-Parsons,Blair Parry,Brendan Lilley,Carl Lodenstein,Brenna N. McKaig,Nicole Charland,Hargun Khanna,Justin D. Margolin,Anna L.K. Gonye,Irena Gushterova,Tom Lasalle,Nihaarika Sharma,Brian C. Russo,Maricarmen Rojas-Lopez,Moshe Sade-Feldman,Kasidet Manakongtreecheep,Jessica Tantivit,Molly Thomas,Nina Bhardwaj,Dan H. Barouch,Alessandro Sette,Alessandro Sette,Marcela V. Maus,Charles M. Rice,Karl R. Clauser,Derin B. Keskin,Daniel C. Pregibon,Nir Hacohen,Nir Hacohen,Steven A. Carr,Jennifer G. Abelin,Mohsan Saeed,Pardis C. Sabeti +62 more
TL;DR: This article reported the first HLA-I immunopeptidome of SARS-CoV-2 in two cell lines at different times post infection using mass spectrometry and found HLAI peptides derived not only from canonical open reading frames (ORFs) but also from internal out-of-frame ORFs in spike and nucleocapsid not captured by current vaccines.
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