Open Access
Van Damme A.
Malou M-Louise Haine,Nicolas Meeùs +1 more
- pp 416-417
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The article was published on 1986-01-01 and is currently open access. It has received 3543 citations till now.read more
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Journal ArticleDOI
Shared principles in NF-kappaB signaling
Matthew S. Hayden,Sankar Ghosh +1 more
TL;DR: The authors synthesize some of the basic principles that have emerged from studies of NF-kappaB, and aim to generate a more unified view of the regulation of the transcription factor.
Journal ArticleDOI
Signaling to NF-kappaB.
Matthew S. Hayden,Sankar Ghosh +1 more
TL;DR: An overview of established NF-kappaB signaling pathways is provided with focus on the current state of research into the mechanisms that regulate IKK activation and NF- kappaB transcriptional activity.
Book ChapterDOI
Interleukin-8 and related chemotactic cytokines--CXC and CC chemokines.
TL;DR: In this paper, the authors focused on interleukin-8 (IL-8) and related chemotactic cytokines, namely, CXC and CC chemokines.
Journal ArticleDOI
Differential Expression of Chemokine Receptors and Chemotactic Responsiveness of Type 1 T Helper Cells (Th1s) and Th2s
Raffaella Bonecchi,Giancarlo Bianchi,Paola Panina Bordignon,Daniele D’Ambrosio,Rosmarie Lang,Alessandro Borsatti,Silvano Sozzani,Paola Allavena,Patrick Gray,Alberto Mantovani,Francesco Sinigaglia +10 more
TL;DR: T helper cells type 1 (Th1s) that produce interferon-γ predominantly mediate cellular immune responses and are involved in the development of chronic inflammatory conditions, whereas Th2s which produce large amounts of IL-4 and IL-5 upregulate IgE production and are prominent in the pathogenesis of allergic diseases.
Journal ArticleDOI
Absence of Monocyte Chemoattractant Protein-1 Reduces Atherosclerosis in Low Density Lipoprotein Receptor–Deficient Mice
Long Gu,Yoshikatsu Okada,Steven K. Clinton,Craig Gerard,Galina K. Sukhova,Peter Libby,Barrett J. Rollins +6 more
TL;DR: Monocyte chemoattractant protein-1 plays a unique and crucial role in the initiation of atherosclerosis and may provide a new therapeutic target in this disorder.
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