Journal ArticleDOI
Wireless implantable microsystems: high-density electronic interfaces to the nervous system
Kensall D. Wise,David J. Anderson,Jamille Farraye Hetke,Daryl R. Kipke,Khalil Najafi +4 more
- Vol. 92, Iss: 1, pp 76-97
TLDR
This paper describes the development of a high-density electronic interface to the central nervous system that permits the long-term monitoring of neural activity in vivo as well as the insertion of electronic signals into neural networks at the cellular level.Abstract:
This paper describes the development of a high-density electronic interface to the central nervous system. Silicon micromachined electrode arrays now permit the long-term monitoring of neural activity in vivo as well as the insertion of electronic signals into neural networks at the cellular level. Efforts to understand and engineer the biology of the implant/tissue interface are also underway. These electrode arrays are facilitating significant advances in our understanding of the nervous system, and merged with on-chip circuitry, signal processing, microfluidics, and wireless interfaces, they are forming the basis for a family of neural prostheses for the possible treatment of disorders such as blindness, deafness, paralysis, severe epilepsy, and Parkinson's disease.read more
Citations
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Journal ArticleDOI
High-Performance Piezoelectric Energy Harvesters and Their Applications
TL;DR: A comprehensive review of piezoelectric energy-harvesting techniques developed in the last decade is presented, identifying four promising applications: shoes, pacemakers, tire pressure monitoring systems, and bridge and building monitoring.
Patent
Implantable Transponder Systems and Methods
TL;DR: In this article, a method and system for providing electrical stimulation to tissue includes implanting one or more battery-free microtransponders having spiral antennas into tissue, where energy is provided wirelessly to the plurality of microtransmoders.
Journal ArticleDOI
Revealing neuronal function through microelectrode array recordings
Marie Engelene J. Obien,Kosmas Deligkaris,Kosmas Deligkaris,Torsten Bullmann,Douglas J. Bakkum,Urs Frey,Urs Frey,Urs Frey +7 more
TL;DR: The ongoing advancements in microelectrode technology are introduced, with focus on achieving higher resolution and quality of recordings by means of monolithic integration with on-chip circuitry.
Journal ArticleDOI
Syringe Injectable Electronics
Jia Liu,Tian-Ming Fu,Zengguang Cheng,Guosong Hong,Tao Zhou,Lihua Jin,Madhavi Duvvuri,Zhe Jiang,Peter B. Kruskal,Chong Xie,Zhigang Suo,Ying Fang,Charles M. Lieber +12 more
TL;DR: This work demonstrates the syringe injection of sub-micrometre-thick, centimetre-scale macroporous mesh electronics through needles with a diameter as small as 100 μm, and demonstrates several applications of syringe-injectable electronics as a general approach for interpenetrating flexible electronics with three-dimensional structures.
Journal ArticleDOI
Chronic neural recording using silicon-substrate microelectrode arrays implanted in cerebral cortex
TL;DR: The results of this study demonstrate that these planar silicon probes are suitable for long-term recording in the cerebral cortex and provide an effective platform technology foundation for microscale intracortical neural interfaces for use in humans.
References
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Direct cortical control of 3d neuroprosthetic devices
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