Women and HIV in Sub-Saharan Africa
TLDR
There is no magic bullet and behavior alone is unlikely to change the course of the epidemic, but substantial progress has been made in biomedical, behavioral and structural strategies for HIV prevention with attendant challenges of developing appropriate HIV prevention packages which take into consideration the socioeconomic and cultural context of women in society at large.Abstract:
Thirty years since the discovery of HIV, the HIV pandemic in sub-Saharan Africa accounts for more than two thirds of the world’s HIV infections. Southern Africa remains the region most severely affected by the epidemic. Women continue to bear the brunt of the epidemic with young women infected almost ten years earlier compared to their male counterparts. Epidemiological evidence suggests unacceptably high HIV prevalence and incidence rates among women. A multitude of factors increase women’s vulnerability to HIV acquisition, including, biological, behavioral, socioeconomic, cultural and structural risks. There is no magic bullet and behavior alone is unlikely to change the course of the epidemic. Considerable progress has been made in biomedical, behavioral and structural strategies for HIV prevention with attendant challenges of developing appropriate HIV prevention packages which take into consideration the socioeconomic and cultural context of women in society at large.read more
Citations
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Journal ArticleDOI
Adeno-Associated Viral Vector Mediated Expression of Broadly- Neutralizing Antibodies Against HIV-Hitting a Fast-Moving Target.
TL;DR: An overview of HIV genetic diversity, AAV vectorology, and anti-HIV bn Abs is provided and the promises and challenges of the application of AAV in the delivery of bnAbs for HIV prevention and therapy are summarized.
Dissertation
Efectividad de un programa de prevención de la transmisión maternoinfantil del VIH en Kenia
TL;DR: Tesis Doctoral leida en la Universidad Rey Juan Carlos de Madrid (RJCD) as mentioned in this paper, 2015. Directores de la Tesis: Julia del Amo Valero y Angel Gil de Miguel
Journal ArticleDOI
Women and HIV: Gender Inequalities of Women Contributing to HIV Pandemic around the Globe
TL;DR: An analytical review of research and literature related to the contributing factors to the rise of HIV in women, treatment and policy development.
Journal ArticleDOI
Seroprevalence and Determinants of Human Immunodeficiency Virus Infection Among Women of Reproductive Age in Mozambique: A Multilevel Analysis
Michael Ekholuenetale,Faith Owunari Benebo,Amadou Barrow,Ashibudike Francis Idebolo,Chimezie Igwegbe Nzoputam +4 more
TL;DR: It was found that having multiple total lifetime number of sexual partners and religion were predisposing factors for HIV infection at individual woman level and community illiteracy, intimate partner violence, poverty and geographical region were associated with HIV infections at community level.
Journal Article
As the HIV Epidemic among Young Women Grows, Can We Look to the SDGs to Reverse the Trend?
TL;DR: To end the growing HIV epidemic among young women, human rights violations must be addressed and the Sustainable Development Goals have the potential to help if political barriers are overcome and a rights-based approach is integrated.
References
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TL;DR: In this article, Antiretroviral therapy that reduces viral replication could limit the transmission of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples.
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Prevention of HIV-1 infection with early antiretroviral therapy
TL;DR: The exciting evidence generated by this paper – that antiretroviral treatment of HIV-1 infection definitively reduces the risk of onward transmission of the virus by 96% – was rightly dubbed Science magazine's ‘Breakthrough of the Year’ in 2011.
Journal ArticleDOI
Antiretroviral prophylaxis for HIV prevention in heterosexual men and women.
Jared M. Baeten,Deborah Donnell,Deborah Donnell,Patrick Ndase,Nelly Mugo,Nelly Mugo,James D. Campbell,Jonathan Wangisi,Jordan W. Tappero,Elizabeth A. Bukusi,Craig R. Cohen,Elly Katabira,Allan R. Ronald,Allan R. Ronald,Elioda Tumwesigye,Edwin Were,Kenneth H. Fife,James Kiarie,James Kiarie,Carey Farquhar,Grace John-Stewart,Aloysious Kakia,Josephine Odoyo,Akasiima Mucunguzi,Edith Nakku-Joloba,Rogers Twesigye,Kenneth Ngure,Cosmas Apaka,Harrison Tamooh,Fridah Gabona,Andrew Mujugira,Dana Panteleeff,Katherine K. Thomas,Lara Kidoguchi,Meighan Krows,Jennifer Revall,Susan Morrison,Harald S. Haugen,Mira Emmanuel-Ogier,Lisa Ondrejcek,Robert W. Coombs,Lisa M. Frenkel,Lisa M. Frenkel,Craig W. Hendrix,Namandjé N. Bumpus,David R. Bangsberg,Jessica E. Haberer,Wendy S. Stevens,Jairam R. Lingappa,Connie Celum +49 more
TL;DR: Oral TDF and TDF-FTC both protect against HIV-1 infection in heterosexual men and women, and both study medications significantly reduced the HIV- 1 incidence among both men andWomen.
Journal ArticleDOI
Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women
Quarraisha Abdool Karim,Salim S. Abdool Karim,Salim S. Abdool Karim,Salim S. Abdool Karim,Janet A. Frohlich,Anneke Grobler,Cheryl Baxter,Leila E. Mansoor,Ayesha B. M. Kharsany,Sengeziwe Sibeko,Koleka Mlisana,Zaheen Omar,Tanuja N. Gengiah,Silvia Maarschalk,Natasha Arulappan,Mukelisiwe Mlotshwa,Lynn Morris,Douglas Taylor +17 more
TL;DR: Tenofovir in a vaginal gel formulation shows significant protection against HIV infection in a randomized control trial, and could potentially fill an important HIV prevention gap, especially for women unable to successfully negotiate mutual monogamy or condom use.
Journal ArticleDOI
Preexposure Prophylaxis for HIV Infection among African Women
Lut Van Damme,Amy Corneli,Khatija Ahmed,Johan Lombaard,Saidi Kapiga,Mookho Malahleha,Rachel Manongi,Jacob Onyango,Lucky Temu,Modie Constance Monedi,Mankalimeng Makanda,Lisa Saylor,Haddie Kiernan,Stella Kirkendale,Christina Wong,Robert M. Grant,Angela D. M. Kashuba,Kavita Nanda,Justin Mandala,Katrien Fransen,Jennifer Deese,Tania Crucitti,Timothy D Mastro,Douglas Taylor +23 more
TL;DR: Prophylaxis with TDF-FTC did not significantly reduce the rate of HIV infection and was associated with increased rates of side effects, as compared with placebo, and drug adherence appeared to be low.
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Antiretroviral prophylaxis for HIV prevention in heterosexual men and women.
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