A
Alexander Dietrich
Researcher at Ludwig Maximilian University of Munich
Publications - 132
Citations - 8613
Alexander Dietrich is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Transient receptor potential channel & TRPC. The author has an hindex of 49, co-authored 120 publications receiving 7689 citations. Previous affiliations of Alexander Dietrich include University of Ulm & University of Marburg.
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Journal ArticleDOI
Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible.
Bernward Hinkes,Roger C. Wiggins,Rasheed Gbadegesin,Christopher N. Vlangos,Dominik Seelow,Gudrun Nürnberg,Puneet Garg,Rakesh Verma,Hassan Chaib,Bethan E. Hoskins,Shazia Ashraf,Christian Becker,Hans Christian Hennies,Meera Goyal,Bryan L. Wharram,Asher D. Schachter,Sudha Mudumana,Iain A. Drummond,Dontscho Kerjaschki,Rüdiger Waldherr,Alexander Dietrich,Fatih Ozaltin,Aysin Bakkaloglu,Roxana Cleper,Roxana Cleper,Lina Basel-Vanagaite,Lina Basel-Vanagaite,Martin Pohl,Martin Griebel,Alexey N. Tsygin,Alper Soylu,Dominik N. Müller,Caroline S. Sorli,Tom D. Bunney,Matilda Katan,Jinhong Liu,Massimo Attanasio,John F. O'Toole,Katrin Hasselbacher,Bettina E. Mucha,Edgar A. Otto,Rannar Airik,Andreas Kispert,Grant G. Kelley,Alan V. Smrcka,Thomas Gudermann,Lawrence B. Holzman,Peter Nürnberg,Friedhelm Hildebrandt +48 more
TL;DR: These findings, together with the zebrafish model of human nephrotic syndrome generated by plce1 knockdown, open new inroads into pathophysiology and treatment mechanisms of nephrotsic syndrome.
Journal ArticleDOI
Increased Vascular Smooth Muscle Contractility in TRPC6 −/− Mice
Alexander Dietrich,Michael Mederos y Schnitzler,Maik Gollasch,Volkmar Gross,Ursula Storch,Galyna Dubrovska,Michael Obst,Eda Yildirim,Birgit Salanova,Hermann Kalwa,Kirill Essin,Olaf Pinkenburg,Friedrich C. Luft,Thomas Gudermann,Lutz Birnbaumer +14 more
TL;DR: It is implied that constitutively active TRPC3-type channels, which are up-regulated in TRPC6-deficient smooth muscle cells, are not able to functionally replace TRPC 6, which has distinct nonredundant roles in the control of vascular smooth muscle tone.
Journal ArticleDOI
TRPC3 Channels Are Required for Synaptic Transmission and Motor Coordination
Jana Hartmann,Elena Dragicevic,Helmuth Adelsberger,Horst A. Henning,Martin Sumser,Joel Abramowitz,Robert Blum,Alexander Dietrich,Marc Freichel,Veit Flockerzi,Lutz Birnbaumer,Arthur Konnerth +11 more
TL;DR: Taken together, the results establish TRPC3 as a new type of postsynaptic channel that mediates mGluR-dependent synaptic transmission in cerebellar Purkinje cells and is crucial for motor coordination.
Journal ArticleDOI
Modulation of Ca2+ entry by polypeptides of the inositol 1,4,5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): Evidence for roles of TRP and IP3R in store depletion-activated Ca2+ entry
Guylain Boulay,Darren Brown,Ning Qin,Meisheng Jiang,Alexander Dietrich,Michael X. Zhu,Zhangguo Chen,Mariel Birnbaumer,Katsuhiko Mikoshiba,Lutz Birnbaumer +9 more
TL;DR: It is concluded that store depletion-activated Ca2+ entry occurs through channels that have TRPs as one of their normal structural components, and that these channels are directly activated by IP3Rs.
Journal ArticleDOI
SwissFEL: The Swiss X-ray Free Electron Laser
Christopher J. Milne,Thomas Schietinger,M. Aiba,Arturo Alarcon,J. Alex,Alexander Anghel,Vladimir Arsov,Carl Beard,Paul Beaud,Simona Bettoni,M. Bopp,H. Brands,Manuel Brönnimann,Ingo Brunnenkant,Marco Calvi,A. Citterio,Paolo Craievich,Marta Csatari Divall,Mark Dällenbach,Michael D’Amico,Andreas Dax,Yunpei Deng,Alexander Dietrich,Roberto Dinapoli,Edwin Divall,Sladana Dordevic,Simon Ebner,Christian Erny,Hansrudolf Fitze,Uwe Flechsig,Rolf Follath,F. Frei,Florian Gärtner,Romain Ganter,Terence Garvey,Zheqiao Geng,I. Gorgisyan,C. Gough,A. Hauff,Christoph P. Hauri,Nicole Hiller,Tadej Humar,Stephan Hunziker,Gerhard Ingold,Rasmus Ischebeck,Markus Janousch,Pavle Juranić,M. Jurcevic,Maik Kaiser,Babak Kalantari,Roger Kalt,B. Keil,Christoph Kittel,Gregor Knopp,W. Koprek,Henrik T. Lemke,Thomas Lippuner,Daniel Llorente Sancho,Florian Löhl,C. Lopez-Cuenca,Fabian Märki,F. Marcellini,G. Marinkovic,Isabelle Martiel,Ralf Menzel,Aldo Mozzanica,Karol Nass,Gian Luca Orlandi,Cigdem Ozkan Loch,Ezequiel Panepucci,Martin Paraliev,Bruce D. Patterson,Bill Pedrini,Marco Pedrozzi,Patrick Pollet,Claude Pradervand,Eduard Prat,Peter Radi,Jean-Yves Raguin,S. Redford,Jens Rehanek,Julien Réhault,Sven Reiche,Matthias Ringele,J. Rittmann,Leonid Rivkin,Albert Romann,Marie Ruat,C. Ruder,Leonardo Sala,Lionel Schebacher,T. Schilcher,Volker Schlott,Thomas J. Schmidt,Bernd Schmitt,Xintian Shi,M. Stadler,L. Stingelin,Werner Sturzenegger,Jakub Szlachetko,D. Thattil,D. Treyer,A. Trisorio,Wolfgang Tron,S. Vetter,Carlo Vicario,Didier Voulot,Meitian Wang,Thierry Zamofing,Christof Zellweger,R. Zennaro,Elke Zimoch,Rafael Abela,Luc Patthey,Hans-Heinrich Braun +114 more
TL;DR: The SwissFEL X-ray Free Electron Laser (XFEL) facility as discussed by the authors started construction at the Paul Scherrer Institute (Villigen, Switzerland) in 2013 and will be ready to accept its first users in 2018 on the Aramis hard Xray branch.