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Alexander Leemans
Researcher at Utrecht University
Publications - 306
Citations - 21500
Alexander Leemans is an academic researcher from Utrecht University. The author has contributed to research in topics: Diffusion MRI & Fractional anisotropy. The author has an hindex of 64, co-authored 289 publications receiving 17932 citations. Previous affiliations of Alexander Leemans include Australian Catholic University & Cardiff University.
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Journal ArticleDOI
Microstructural maturation of the human brain from childhood to adulthood.
TL;DR: Differences observed in developmental timing suggest a pattern of maturation in which areas with fronto-temporal connections develop more slowly than other regions, which is consistent with previous postmortem and imaging studies.
Journal ArticleDOI
The B-matrix must be rotated when correcting for subject motion in DTI data.
Alexander Leemans,Derek K. Jones +1 more
TL;DR: A systematic study to investigate the effect of neglecting to reorient the B‐matrix on DTI data during motion correction is presented and the consequences for diffusion fiber tractography are discussed.
Journal ArticleDOI
The challenge of mapping the human connectome based on diffusion tractography
Klaus H. Maier-Hein,Peter F. Neher,Jean-Christophe Houde,Marc-Alexandre Côté,Eleftherios Garyfallidis,Jidan Zhong,Maxime Chamberland,Fang-Cheng Yeh,Ying-Chia Lin,Qing Ji,Wilburn E. Reddick,John O. Glass,David Qixiang Chen,Yuanjing Feng,Chengfeng Gao,Ye Wu,Jieyan Ma,H Renjie,Qiang Li,Carl-Fredrik Westin,Samuel Deslauriers-Gauthier,J. Omar Ocegueda Gonzalez,Michael Paquette,Samuel St-Jean,Gabriel Girard,François Rheault,Jasmeen Sidhu,Chantal M. W. Tax,Fenghua Guo,Hamed Y. Mesri,Szabolcs David,Martijn Froeling,Anneriet M. Heemskerk,Alexander Leemans,Arnaud Boré,Basile Pinsard,Christophe Bedetti,Matthieu Desrosiers,Simona M. Brambati,Julien Doyon,Alessia Sarica,Roberta Vasta,Antonio Cerasa,Aldo Quattrone,Jason D. Yeatman,Ali R. Khan,Wes Hodges,Simon Alexander,David Romascano,Muhamed Barakovic,Anna Auría,Oscar Esteban,Alia Lemkaddem,Jean-Philippe Thiran,Hasan Ertan Cetingul,Benjamin L. Odry,Boris Mailhe,Mariappan S. Nadar,Fabrizio Pizzagalli,Gautam Prasad,Julio E. Villalon-Reina,Justin Galvis,Paul M. Thompson,Francisco De Santiago Requejo,Pedro Luque Laguna,Luis Miguel Lacerda,Rachel Barrett,Flavio Dell'Acqua,Marco Catani,Laurent Petit,Emmanuel Caruyer,Alessandro Daducci,Tim B. Dyrby,Tim Holland-Letz,Claus C. Hilgetag,Bram Stieltjes,Maxime Descoteaux +76 more
TL;DR: The encouraging finding that most state-of-the-art algorithms produce tractograms containing 90% of the ground truth bundles (to at least some extent) is reported, however, the same tractograms contain many more invalid than valid bundles, and half of these invalid bundles occur systematically across research groups.
ExploreDTI: a graphical toolbox for processing, analyzing, and visualizing diffusion MR data
TL;DR: The ExploreDTI toolbox as mentioned in this paper is a non-commercial package that combines many of the key diffusion processing tools that have appeared in the recent literature, but which have not necessarily been widely available.
Journal ArticleDOI
Investigating the prevalence of complex fiber configurations in white matter tissue with diffusion magnetic resonance imaging.
TL;DR: More robust estimates of the proportion of affected voxels, the number of fiber orientations within each WM voxel, and the impact on tensor‐derived analyses are provided, using large, high‐quality diffusion‐weighted data sets, with reconstruction parameters optimized specifically for this task.