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Anja Richter
Researcher at Humboldt University of Berlin
Publications - 28
Citations - 1547
Anja Richter is an academic researcher from Humboldt University of Berlin. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 13, co-authored 16 publications receiving 1083 citations. Previous affiliations of Anja Richter include Free University of Berlin & German Cancer Research Center.
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Journal ArticleDOI
Microanatomy at Cellular Resolution and Spatial Order of Physiological Differentiation in a Bacterial Biofilm
TL;DR: This study reveals the microanatomy and microphysiology of an Escherichia coli macrocolony biofilm at an unprecedented cellular resolution, with physiologically different zones and strata forming as a function of known global regulatory networks that respond to biofilm-intrinsic gradients of nutrient supply.
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Cellulose as an Architectural Element in Spatially Structured Escherichia coli Biofilms
TL;DR: In this article, the authors used scanning electron and fluorescence microscopy to locate cellulose filaments, sheets and nanocomposites with curli fibers within the physiologically two-layered macrocolony biofilms of E. coli K-12 strain W3110.
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A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.
Jakob Kreye,S. Momsen Reincke,Hans Christian Kornau,Hans Christian Kornau,Elisa Sanchez-Sendin,Elisa Sanchez-Sendin,Elisa Sanchez-Sendin,Victor M. Corman,Hejun Liu,Meng Yuan,Nicholas C. Wu,Xueyong Zhu,Chang-Chun D Lee,Jakob Trimpert,Markus Höltje,Kristina Dietert,Laura Stöffler,Laura Stöffler,Niels von Wardenburg,Niels von Wardenburg,Scott van Hoof,Scott van Hoof,Scott van Hoof,Marie A Homeyer,Marie A Homeyer,Julius Hoffmann,Julius Hoffmann,Azza Abdelgawad,Achim D. Gruber,Luca D. Bertzbach,Daria Vladimirova,Lucie Y Li,Lucie Y Li,Paula Charlotte Barthel,Karl Skriner,Andreas C. Hocke,Stefan Hippenstiel,Martin Witzenrath,Norbert Suttorp,Florian Kurth,Florian Kurth,Christiana Franke,Matthias Endres,Dietmar Schmitz,Dietmar Schmitz,Lara Maria Jeworowski,Anja Richter,Marie Luisa Schmidt,Tatjana Schwarz,Marcel A. Müller,Christian Drosten,Daniel Wendisch,Leif E. Sander,Nikolaus Osterrieder,Nikolaus Osterrieder,Ian A. Wilson,Harald Prüss,Harald Prüss,Harald Prüss +58 more
TL;DR: Results show that non-self-reactive virus-neutralizing mAbs elicited during SARS-CoV-2 infection are a promising therapeutic strategy and should be guided by immunization strategies.
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SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals.
Nils C. Gassen,Jan Papies,Jan Papies,Thomas Bajaj,Jackson Emanuel,Jackson Emanuel,Frederik Dethloff,Robert Lorenz Chua,Jakob Trimpert,Nicolas Heinemann,Nicolas Heinemann,Christine Niemeyer,Friderike Weege,Friderike Weege,Katja Hönzke,Tom Aschman,Daniel E. Heinz,Katja Weckmann,Tim Ebert,Andreas Zellner,M. Lennarz,Emanuel Wyler,Simon Schroeder,Simon Schroeder,Anja Richter,Anja Richter,Daniela Niemeyer,Daniela Niemeyer,Karen Hoffmann,Thomas F. Meyer,Frank L. Heppner,Frank L. Heppner,Victor M. Corman,Victor M. Corman,Markus Landthaler,Markus Landthaler,Andreas C. Hocke,Markus Morkel,Markus Morkel,Nikolaus Osterrieder,Nikolaus Osterrieder,Christian Conrad,Roland Eils,Roland Eils,Helena Radbruch,Patrick Giavalisco,Christian Drosten,Christian Drosten,Marcel A. Müller +48 more
TL;DR: In this paper, the authors show that SARS-CoV-2 infection modulates cellular metabolism and limits autophagy, and identify druggable host pathways for virus inhibition.
Journal ArticleDOI
More than Enzymes That Make or Break Cyclic Di-GMP-Local Signaling in the Interactome of GGDEF/EAL Domain Proteins of Escherichia coli.
Olga Sarenko,Gisela Klauck,Franziska M Wilke,Vanessa Pfiffer,Anja Richter,Susanne Herbst,Volkhard Kaever,Regine Hengge +7 more
TL;DR: The results provide the basis for a novel model of local c-di-GMP signaling in which a single strongly expressed master PDE, PdeH, dynamically eradicates global effects of several DGCs by strongly draining the global c- di-G MP pool and thereby restricting these D GCs to serving as local c+GMP sources that activate specific colocalized effector/target systems.