Chi Wai Yip

TL;DR: This work integrates multiple transcript collections to generate a comprehensive atlas of 27,919 human lncRNA genes with high-confidence 5′ ends and expression profiles across 1,829 samples from the major human primary cell types and tissues, identifying 19,175 potentially functional lncRNAs in the human genome.

TL;DR: The largest-to-date lncRNA knockdown data set with molecular phenotyping is disseminated for further exploration and functional roles for ZNF213-AS1 and lnc-KHDC3L-2 are highlighted.

TL;DR: The sixth (latest) edition of the FANTOM project was launched to assess the function of human long non-coding RNAs (lncRNAs), and the updated FANTOM web resource is publicly available at https://fantom.riken.jp.

TL;DR: The utility of the FC-R2 atlas is demonstrated by reproducing key findings from published large studies and by generating new results across normal and diseased human samples, which will empower other researchers to investigate functions and biological roles of both known coding genes and novel lncRNAs.

TL;DR: Combining cellular and molecular profiling provided a powerful approach to unravel the distinct functions of lncRNAs, which are highlighted with specific functional roles for ZNF213-AS1 and lnc-KHDC3L-2.