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Chih-Chuang Liaw

Researcher at National Sun Yat-sen University

Publications -  66
Citations -  4094

Chih-Chuang Liaw is an academic researcher from National Sun Yat-sen University. The author has contributed to research in topics: Chemistry & Apoptosis. The author has an hindex of 24, co-authored 60 publications receiving 2920 citations. Previous affiliations of Chih-Chuang Liaw include University of North Carolina at Chapel Hill & Kaohsiung Medical University.

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Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

Mingxun Wang, +135 more
- 01 Aug 2016 - 
TL;DR: In GNPS, crowdsourced curation of freely available community-wide reference MS libraries will underpin improved annotations and data-driven social-networking should facilitate identification of spectra and foster collaborations.
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Influenza A (H1N1) Antiviral and Cytotoxic Agents from Ferula assa-foetida

TL;DR: Two new sesquiterpene coumarins were isolated from a CHCl(3)-soluble extract of Ferula assa-foetida through bioassay-guided fractionation and showed greater potency against influenza A virus than amantadine and exhibited the best potency against HepG2, Hep3B, and MCF-7 cancer cell lines.
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Historic Perspectives on Annonaceous Acetogenins from the Chemical Bench to Preclinical Trials

TL;DR: The purpose of this review is to give an account of recent studies on this class of compounds and their analogues, which will aid not only in clarifying how the Annonaceous acetogenins act but also in establishing principles for the further development of thisclass of compounds.
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Anticancer drugs for the modulation of endoplasmic reticulum stress and oxidative stress.

TL;DR: This review summarizes the current understanding of the interplay between ER stress and ROS and discusses how damage-associated molecular patterns (DAMPs) function as modulators of immunogenic cell death and how natural products and drugs have shown potential in regulating ER Stress and ROS in different cancer cell lines.
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Asperjinone, a nor-neolignan, and terrein, a suppressor of ABCG2-expressing breast cancer cells, from thermophilic Aspergillus terreus.

TL;DR: Treatment with terrein significantly suppressed growth of ABCG2-expressing breast cancer cells, and this suppressive effect was achieved by inducing apoptosis via activating the caspase-7 pathway and inhibiting the Akt signaling pathway, which led to a decrease in ABCG 2- expressing cells and a reduction in the side-population phenotype.