Delphine Parrot

TL;DR: In GNPS, crowdsourced curation of freely available community-wide reference MS libraries will underpin improved annotations and data-driven social-networking should facilitate identification of spectra and foster collaborations.

TL;DR: It is clear that SSU rRNA based operational taxonomy units, even at the most stringent cut-off can represent multiple bacterial species, and that at least for the case of Streptomyces, strain de-replication based on SSU gene sequences prior to screening for bioactive molecules can miss potentially interesting novel molecules produced by this group that is notorious for the production of drug-leads.

TL;DR: The Global Natural Products Social Molecular Networking (GNPS) as discussed by the authors is an open-access knowledge base for community wide organization and sharing of raw, processed or identified tandem mass (MS/MS) spectrometry data.

TL;DR: This review summarizes the current state-of-the-art IMS methods with a strong focus on desorption electrospray ionization (DESI)-IMS, and discusses the present applications of DESI-IMS in natural product research.

TL;DR: Results show that littoral lichens are a source of diverse potentially bioactive Actinobacteria, and the diversity was most influenced by the selective media rather than lichen species or the level of lichen thallus association.