E
Elsio A. Wunder
Researcher at Yale University
Publications - 81
Citations - 2704
Elsio A. Wunder is an academic researcher from Yale University. The author has contributed to research in topics: Leptospira & Leptospira interrogans. The author has an hindex of 25, co-authored 69 publications receiving 1950 citations. Previous affiliations of Elsio A. Wunder include Oswaldo Cruz Foundation & Universidade Federal do Rio Grande do Sul.
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Journal ArticleDOI
Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico.
Davide F. Robbiani,Leonia Bozzacco,Jennifer R. Keeffe,Ricardo Khouri,Priscilla C. Olsen,Anna Gazumyan,Dennis Schaefer-Babajew,Santiago Ávila-Ríos,Lilian Nogueira,Roshni Patel,Stephanie A. Azzopardi,Lion F.K. Uhl,Mohsan Saeed,Edgar E. Sevilla-Reyes,Marianna Agudelo,Kai Hui Yao,Jovana Golijanin,Harry B. Gristick,Yu E. Lee,Arlene Hurley,Marina Caskey,Joy A. Pai,Thiago Y. Oliveira,Elsio A. Wunder,Elsio A. Wunder,Gielson Almeida do Sacramento,Nivison Nery,Cibele Orge,Federico Costa,Federico Costa,Federico Costa,Mitermayer G. Reis,Mitermayer G. Reis,Mitermayer G. Reis,Neena M. Thomas,Thomas Eisenreich,Daniel M. Weinberger,Antônio Raimundo Pinto de Almeida,Anthony P. West,Charles M. Rice,Pamela J. Bjorkman,Gustavo Reyes-Terán,Albert I. Ko,Albert I. Ko,Margaret R. MacDonald,Michel C. Nussenzweig,Michel C. Nussenzweig +46 more
TL;DR: High neutralizing responses to ZIKV are associated with pre-existing reactivity to DENV1 in humans, andStructural analyses reveal the mechanism of recognition of the ZEDIII lateral ridge by VH3-23/VK1-5 antibodies.
Journal ArticleDOI
What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira.
Derrick E. Fouts,Michael A. Matthias,Haritha Adhikarla,Ben Adler,Luciane Amorim-Santos,Luciane Amorim-Santos,Douglas E. Berg,Dieter M. Bulach,Alejandro Buschiazzo,Yung Fu Chang,Renee L. Galloway,David A. Haake,Daniel H. Haft,Rudy A. Hartskeerl,Albert I. Ko,Albert I. Ko,Paul N. Levett,James Matsunaga,Ariel E. Mechaly,Jonathan M. Monk,Ana L. T. O. Nascimento,Ana L. T. O. Nascimento,Karen E. Nelson,Bernhard O. Palsson,Sharon J. Peacock,Mathieu Picardeau,Jessica N. Ricaldi,Janjira Thaipandungpanit,Elsio A. Wunder,Elsio A. Wunder,X. Frank Yang,Jun-Jie Zhang,Joseph M. Vinetz,Joseph M. Vinetz,Joseph M. Vinetz +34 more
TL;DR: Insight is provided into mechanisms by which bacterial pathogens adapt to mammalian hosts and large scale changes in infectious (pathogenic and intermediately pathogenic) vs. non-infectious Leptospira are identified, which provides new insights into the evolution of a genus of bacterial pathogens.
Journal ArticleDOI
Impact of preexisting dengue immunity on Zika virus emergence in a dengue endemic region
Isabel Rodriguez-Barraquer,Federico Costa,Federico Costa,Federico Costa,Eduardo J. M. Nascimento,Nivison Ruy Rocha Nery Junior,Nivison Ruy Rocha Nery Junior,Priscila M. S. Castanha,Priscila M. S. Castanha,Gielson Almeida do Sacramento,Jaqueline S. Cruz,Mayara Carvalho,Daiana De Olivera,José E. Hagan,José E. Hagan,Haritha Adhikarla,Elsio A. Wunder,Elsio A. Wunder,Danilo F. Coêlho,Danilo F. Coêlho,Sasha R. Azar,Shannan L. Rossi,Nikos Vasilakis,Scott C. Weaver,Guilherme S. Ribeiro,Guilherme S. Ribeiro,Angel Balmaseda,Eva Harris,Maurício Lacerda Nogueira,Mitermayer G. Reis,Mitermayer G. Reis,Mitermayer G. Reis,Ernesto T. A. Marques,Ernesto T. A. Marques,Derek A. T. Cummings,Albert I. Ko,Albert I. Ko +36 more
TL;DR: Zika transmission within a Brazilian slum community indicates that prior dengue immunity and local variations influence transmission, and the landscape of ZIKV immunity that now exists may affect the risk for future transmission.
Journal ArticleDOI
Spatiotemporal Determinants of Urban Leptospirosis Transmission: Four-Year Prospective Cohort Study of Slum Residents in Brazil
José E. Hagan,Paula Moraga,Federico Costa,Federico Costa,Federico Costa,Nicolas Capian,Guilherme S. Ribeiro,Guilherme S. Ribeiro,Elsio A. Wunder,Ridalva Dias Martins Felzemburgh,Renato Barbosa Reis,Nivison Nery,Francisco S. Santana,Deborah Bittencourt Mothé Fraga,Balbino L. dos Santos,Andréia C. Santos,Adriano Queiroz,Wagner de Souza Tassinari,Marilia Sá Carvalho,Mitermayer G. Reis,Peter J. Diggle,Albert I. Ko,Albert I. Ko +22 more
TL;DR: It is suggested that topographic factors such as household elevation and inadequate drainage increase risk by promoting contact with mud and suggest that the soil-water interface serves as the environmental reservoir for spillover transmission.
Journal ArticleDOI
De novo emergence of a remdesivir resistance mutation during treatment of persistent SARS-CoV-2 infection in an immunocompromised patient: a case report
S. Gandhi,Jon Klein,Alexander J Robertson,Mario A. Peña-Hernández,Michelle Lin,Pavitra Roychoudhury,Peiwen Lu,John Fournier,David Ferguson,S. A. Mohamed Bakhash,M. Catherine Muenker,Ariktha Srivathsan,Elsio A. Wunder,N. Kerantzas,Wenshuai Wang,Brett D. Lindenbach,Anna Marie Pyle,Craig B. Wilen,Onyema Ogbuagu,Alexander L. Greninger,Akiko Iwasaki,Wade L. Schulz,Albert I. Ko +22 more
TL;DR: In this paper , a case of an immunocompromised patient with acquired B-cell deficiency who developed an indolent, protracted course of SARS-CoV-2 infection was presented.