M
Margot Sunshine
Researcher at National Institutes of Health
Publications - 21
Citations - 3786
Margot Sunshine is an academic researcher from National Institutes of Health. The author has contributed to research in topics: BioPAX : Biological Pathways Exchange & Gene. The author has an hindex of 17, co-authored 21 publications receiving 3287 citations. Previous affiliations of Margot Sunshine include SRA International & General Dynamics.
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Journal ArticleDOI
GoMiner: a resource for biological interpretation of genomic and proteomic data
Barry R. Zeeberg,Weimin Feng,Geoffrey D. Wang,May D. Wang,Anthony T. Fojo,Margot Sunshine,Sudarshan Narasimhan,David W. Kane,William C. Reinhold,Samir Lababidi,Kimberly J. Bussey,Joseph Riss,J. Carl Barrett,John N. Weinstein +13 more
TL;DR: GoMiner, a program package that organizes lists of 'interesting' genes for biological interpretation in the context of the Gene Ontology, provides quantitative and statistical output files and two useful visualizations.
Journal ArticleDOI
The BioPAX community standard for pathway data sharing
Emek Demir,Emek Demir,Michael P. Cary,Suzanne M. Paley,Ken Fukuda,Christian Lemer,Imre Vastrik,Guanming Wu,Peter D'Eustachio,Carl F. Schaefer,Joanne S. Luciano,Frank Schacherer,Irma Martínez-Flores,Zhenjun Hu,Verónica Jiménez-Jacinto,Geeta Joshi-Tope,Kumaran Kandasamy,Alejandra López-Fuentes,Huaiyu Mi,Elgar Pichler,Igor Rodchenkov,Andrea Splendiani,Andrea Splendiani,Sasha Tkachev,Jeremy Zucker,Gopal R. Gopinath,Harsha Rajasimha,Harsha Rajasimha,Ranjani Ramakrishnan,Imran Shah,Mustafa H Syed,Nadia Anwar,Özgün Babur,Özgün Babur,Michael L. Blinov,Erik Brauner,Dan Corwin,Sylva L. Donaldson,Frank Gibbons,Robert N. Goldberg,Peter Hornbeck,Augustin Luna,Peter Murray-Rust,Eric K. Neumann,Oliver Reubenacker,Matthias Samwald,Matthias Samwald,Martijn P. van Iersel,Sarala M. Wimalaratne,Keith Allen,Burk Braun,Michelle Whirl-Carrillo,Kei-Hoi Cheung,Kam D. Dahlquist,Andrew Finney,Marc Gillespie,Elizabeth M. Glass,Li Gong,Robin Haw,Michael Honig,Olivier Hubaut,David W. Kane,Shiva Krupa,Martina Kutmon,Julie Leonard,Debbie Marks,David Merberg,Victoria Petri,Alexander R. Pico,Dean Ravenscroft,Liya Ren,Nigam H. Shah,Margot Sunshine,Rebecca Tang,Ryan Whaley,Stan Letovksy,Kenneth H. Buetow,Andrey Rzhetsky,Vincent Schächter,Bruno S. Sobral,Ugur Dogrusoz,Shannon K. McWeeney,Mirit I. Aladjem,Ewan Birney,Julio Collado-Vides,Susumu Goto,Michael Hucka,Nicolas Le Novère,Natalia Maltsev,Akhilesh Pandey,Paul Thomas,Edgar Wingender,Peter D. Karp,Chris Sander,Gary D. Bader +94 more
TL;DR: Thousands of interactions, organized into thousands of pathways, from many organisms are available from a growing number of databases, and this large amount of pathway data in a computable form will support visualization, analysis and biological discovery.
Journal ArticleDOI
CellMiner: a web-based suite of genomic and pharmacologic tools to explore transcript and drug patterns in the NCI-60 cell line set
William C. Reinhold,Margot Sunshine,Margot Sunshine,Hongfang Liu,Sudhir Varma,Kurt W. Kohn,Joel Morris,James H. Doroshow,Yves Pommier +8 more
TL;DR: A CellMiner web application is introduced designed to improve the use of the extensive NCI-60 cell line database for discovery by creating web-based processes that are rapid, flexible, and readily applied by users without bioinformatics expertise.
Journal ArticleDOI
High-Throughput GoMiner, an 'industrial-strength' integrative gene ontology tool for interpretation of multiple-microarray experiments, with application to studies of Common Variable Immune Deficiency (CVID)
Barry R. Zeeberg,Haiying Qin,Sudarshan Narasimhan,Margot Sunshine,Hong Cao,David W. Kane,Mark Reimers,Robert M. Stephens,David Bryant,Stanley K. Burt,Eldad Elnekave,Danielle M. Hari,Thomas A. Wynn,Charlotte Cunningham-Rundles,Donn M. Stewart,David E. Nelson,John N. Weinstein +16 more
TL;DR: High-Throughput GoMiner achieves the desired goal of providing a computational resource that automates the analysis of multiple microarrays and then integrates the results across all of them in useful exportable output files and visualizations.
Journal ArticleDOI
CellMiner: a relational database and query tool for the NCI-60 cancer cell lines
Uma Shankavaram,Sudhir Varma,David W. Kane,Margot Sunshine,Krishna K. Chary,William C. Reinhold,Yves Pommier,John N. Weinstein,John N. Weinstein +8 more
TL;DR: CellMiner is a relational database tool for storing, querying, integrating, and downloading molecular profile data on the NCI-60 and other cancer cell types and provides a template to use in providing such functionality for other Molecular profile data generated by academic institutions, public projects, or the private sector.