Christian Lemer

TL;DR: Thousands of interactions, organized into thousands of pathways, from many organisms are available from a growing number of databases, and this large amount of pathway data in a computable form will support visualization, analysis and biological discovery.

TL;DR: The Comprehensive Yeast Genome Database (CYGD) compiles a comprehensive data resource for information on the cellular functions of the yeast Saccharomyces cerevisiae and related species, chosen as the best understood model organism for eukaryotes.

TL;DR: It is found that threading methods are capable of identifying the correct fold in many cases, but not reliably enough as yet, and threading can presently not be relied upon to derive a detailed 3D model from the amino acid sequence.

TL;DR: The aMAZ LightBench is a web interface to the aMAZE relational database, which contains information on gene expression, catalysed chemical reactions, regulatory interactions, protein assembly, as well as metabolic and signal transduction pathways.

TL;DR: The scope of BioPAX is expanded to include representation of molecular binding interactions, protein post-translational modifications, basic experimental descriptions, and hierarchical pathways, which will increase access to and uniformity of pathway data from varied sources, thus increasing the efficiency of computational pathway research.