N
Nathalia A. Giese
Researcher at University Hospital Heidelberg
Publications - 161
Citations - 9312
Nathalia A. Giese is an academic researcher from University Hospital Heidelberg. The author has contributed to research in topics: Pancreatic cancer & Cancer. The author has an hindex of 51, co-authored 150 publications receiving 8107 citations. Previous affiliations of Nathalia A. Giese include French Institute of Health and Medical Research & Heidelberg University.
Papers
More filters
Journal ArticleDOI
Consensus guidelines for the detection of immunogenic cell death
Oliver Kepp,Laura Senovilla,Ilio Vitale,Erika Vacchelli,Sandy Adjemian,Patrizia Agostinis,Lionel Apetoh,Fernando Aranda,Vincenzo Barnaba,Norma Bloy,Laura Bracci,Karine Breckpot,David Brough,Aitziber Buqué,Maria G. Castro,Mara Cirone,María Isabel Colombo,Isabelle Cremer,Sandra Demaria,Luciana Dini,Aristides G. Eliopoulos,Alberto Faggioni,Silvia C. Formenti,Jitka Fucikova,Lucia Gabriele,Udo S. Gaipl,Jérôme Galon,Abhishek D. Garg,François Ghiringhelli,Nathalia A. Giese,Zong Sheng Guo,Akseli Hemminki,Martin Herrmann,James W. Hodge,Stefan Holdenrieder,Jamie Honeychurch,Hong-Min Hu,Xing Huang,Timothy M Illidge,Koji Kono,Mladen Korbelik,Dmitri V. Krysko,Sherene Loi,Pedro R. Lowenstein,Enrico Lugli,Yuting Ma,Frank Madeo,Angelo A. Manfredi,Isabelle Martins,Domenico Mavilio,Laurie Menger,Nicolò Merendino,Michael Michaud,Grégoire Mignot,Karen L. Mossman,Gabriele Multhoff,Rudolf Oehler,Fabio Palombo,Theocharis Panaretakis,Jonathan Pol,Enrico Proietti,Jean-Ehrland Ricci,Chiara Riganti,Patrizia Rovere-Querini,Anna Rubartelli,Antonella Sistigu,Mark J. Smyth,Juergen Sonnemann,Radek Spisek,John Stagg,Abdul Qader Sukkurwala,Eric Tartour,Andrew Thorburn,Stephen H. Thorne,Peter Vandenabeele,Francesca Velotti,Samuel T Workenhe,Haining Yang,Wei-Xing Zong,Laurence Zitvogel,Guido Kroemer,Lorenzo Galluzzi +81 more
TL;DR: Strategies conceived to detect surrogate markers of ICD in vitro and to screen large chemical libraries for putative I CD inducers are outlined, based on a high-content, high-throughput platform that was recently developed.
Journal ArticleDOI
Combined evaluation of a panel of protein and miRNA serum-exosome biomarkers for pancreatic cancer diagnosis increases sensitivity and specificity.
Bindhu Madhavan,Shijing Yue,Uwe Galli,Sanyukta Rana,Wolfgang Gross,Miryam Müller,Nathalia A. Giese,Holger Kalthoff,Thomas Becker,Markus W. Büchler,Margot Zöller +10 more
TL;DR: The concomitant evaluation of PaCIC and PaCa‐related miRNA marker panels awaits retrospective analyses of larger cohorts, as it should allow for a highly sensitive, minimally‐invasive PaCa diagnostics.
Journal ArticleDOI
The Activated Stroma Index Is a Novel and Independent Prognostic Marker in Pancreatic Ductal Adenocarcinoma
Mert Erkan,Christoph W. Michalski,Christoph W. Michalski,Simon Rieder,Carolin Reiser-Erkan,Ivane Abiatari,Armin Kolb,Nathalia A. Giese,Irene Esposito,Helmut Friess,Jörg Kleeff +10 more
TL;DR: The activated stroma index (ASI) is a novel independent prognostic marker in PDAC in cases undergoing surgery and highlights the impact of the microenvironment in cancer progression and on patient survival.
Journal ArticleDOI
Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity.
Mert Erkan,Jörg Kleeff,Andre Gorbachevski,Carolin Reiser,Tomas Mitkus,Irene Esposito,Thomas Giese,Markus W. Büchler,Nathalia A. Giese,Helmut Friess +9 more
TL;DR: Once stimulated by cancer cells, PSCs remain active via an autocrine periostin loop even under radiotherapy and produce excessive extracellular matrix proteins, creating a tumor-supportive microenvironment.
Journal ArticleDOI
Inhibition of Heme Oxygenase-1 Increases Responsiveness of Pancreatic Cancer Cells to Anticancer Treatment
Pascal O. Berberat,Zilvinas Dambrauskas,Antanas Gulbinas,Thomas Giese,Nathalia A. Giese,Beat M. Künzli,Frank Autschbach,Stefen Meuer,Markus W. Büchler,Helmut Friess +9 more
TL;DR: Targeted knockdown of HO-1 expression led to pronounced growth inhibition of the pancreatic cancer cells and made tumor cells significantly more sensitive to radiotherapy and chemotherapy.