H
Heike Münzberg
Researcher at Pennington Biomedical Research Center
Publications - 70
Citations - 5402
Heike Münzberg is an academic researcher from Pennington Biomedical Research Center. The author has contributed to research in topics: Leptin & Energy homeostasis. The author has an hindex of 29, co-authored 66 publications receiving 4272 citations.
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Journal ArticleDOI
A guide to analysis of mouse energy metabolism
Matthias H. Tschöp,John R. Speakman,John R. Speakman,Jonathan R.S. Arch,Johan Auwerx,Jens C. Brüning,Lawrence Chan,Robert H. Eckel,Robert V. Farese,Jose E. Galgani,Catherine Hambly,Mark A. Herman,Tamas L. Horvath,Barbara B. Kahn,Sara C. Kozma,Eleftheria Maratos-Flier,Timo D. Müller,Heike Münzberg,Paul T. Pfluger,Leona Plum,Marc L. Reitman,Kamal Rahmouni,Gerald I. Shulman,George Thomas,C. Ronald Kahn,Eric Ravussin +25 more
TL;DR: A consolidated view of the complexity and challenges of designing studies for measurement of energy metabolism in mouse models is presented, including a practical guide to the assessment of energy expenditure, energy intake and body composition and statistical analysis thereof.
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Canonical Nlrp3 Inflammasome Links Systemic Low-Grade Inflammation to Functional Decline in Aging
Yun-Hee Youm,Ryan W. Grant,Laura R. McCabe,Diana C. Albarado,Kim Y. Nguyen,Anthony Ravussin,Paul J. Pistell,Susan Newman,Renee T. Carter,Amanda Laque,Heike Münzberg,Clifford J. Rosen,Donald K. Ingram,J. Michael Salbaum,Vishwa Deep Dixit,Vishwa Deep Dixit +15 more
TL;DR: Nlrp3 inflammasome is revealed as an upstream target that controls age-related inflammation and an innovative therapeutic strategy to lower NLRp3 activity to delay multiple age- related chronic diseases is offered.
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FGF21 is an endocrine signal of protein restriction
Thomas Laeger,Tara M. Henagan,Diana C. Albarado,Leanne M. Redman,George A. Bray,Robert C. Noland,Heike Münzberg,Susan M. Hutson,Thomas W. Gettys,Michael W. Schwartz,Christopher D. Morrison +10 more
TL;DR: FGF21 represents an endocrine signal of protein restriction, which acts to coordinate metabolism and growth during periods of reduced protein intake and that FGF21 is required for behavioral and metabolic responses to protein restriction.
Journal ArticleDOI
Structure, production and signaling of leptin
TL;DR: This review will highlight the current knowledge about the hormone leptin, its signaling pathways and its central actions to mediate distinct physiological functions.
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Leptin and Insulin Act on POMC Neurons to Promote the Browning of White Fat
Garron T. Dodd,Stephanie Sylvie Decherf,Kim Loh,Stephanie E. Simonds,Florian Wiede,Eglantine Balland,Troy L. Merry,Heike Münzberg,Zhong Yin Zhang,Barbara B. Kahn,Benjamin G. Neel,Kendra K. Bence,Zane B. Andrews,Michael A. Cowley,Tony Tiganis +14 more
TL;DR: It is reported that insulin and leptin act together on hypothalamic neurons to promote WAT browning and weight loss, and a homeostatic mechanism for coordinating the status of energy stores, as relayed by insulin andptin, with the central control of WATbrowning is identified.