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Hong Wang

Researcher at Monell Chemical Senses Center

Publications -  21
Citations -  1213

Hong Wang is an academic researcher from Monell Chemical Senses Center. The author has contributed to research in topics: Taste & Taste receptor. The author has an hindex of 14, co-authored 21 publications receiving 908 citations.

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Journal ArticleDOI

Pseudogenization of a Sweet-Receptor Gene Accounts for Cats' Indifference toward Sugar

TL;DR: The sweet-receptor genes of domestic cats as well as those of other members of the Felidae family of obligate carnivores, tiger and cheetah are characterized and it is concluded that cat Tas1r3 is an apparently functional and expressed receptor but thatCat Tas1 r2 is an unexpressed pseudogene.
Journal ArticleDOI

Inflammation and taste disorders: mechanisms in taste buds

TL;DR: Data suggest that TLR and IFN pathways function collaboratively in recognizing pathogens and mediating inflammatory responses in taste tissue, and this process may interfere with normal taste transduction and taste bud cell turnover and contributes to the development of taste disorders.
Posted ContentDOI

More than smell. COVID-19 is associated with severe impairment of smell, taste, and chemesthesis

Valentina Parma, +121 more
- 24 May 2020 - 
TL;DR: The results show that COVID-19-associated chemosensory impairment is not limited to smell, but also affects taste and chemesthesis, and suggest that SARS-CoV-2 infection may disrupt sensory-neural mechanisms.
Journal ArticleDOI

Taste Bud Homeostasis in Health, Disease, and Aging

TL;DR: The mammalian taste bud is an onion-shaped epithelial structure with 50-100 tightly packed cells, including taste receptor cells, supporting cells, and basal cells, which contribute to taste dysfunction associated with disease and aging.
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Bitter peptides activate hTAS2Rs, the human bitter receptors.

TL;DR: The results showed that these bitter peptides, as well as many other bitter compounds, activate hTAS2Rs, suggesting that humans utilize these hTas2Rs to recognize and perceive the structure and bitterness of peptides.