J
Jo Vandesompele
Researcher at Ghent University
Publications - 406
Citations - 67052
Jo Vandesompele is an academic researcher from Ghent University. The author has contributed to research in topics: Neuroblastoma & microRNA. The author has an hindex of 88, co-authored 383 publications receiving 59368 citations. Previous affiliations of Jo Vandesompele include Washington University in St. Louis & Ghent University Hospital.
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Journal ArticleDOI
Minimally invasive classification of paediatric solid tumours using reduced representation bisulphite sequencing of cell-free DNA: a proof-of-principle study
Ruben Van Paemel,Ruben Van Paemel,Andries De Koker,Charlotte Vandeputte,Lieke M. J. van Zogchel,Tim Lammens,Tim Lammens,Genevieve Laureys,Genevieve Laureys,Jo Vandesompele,Gudrun Schleiermacher,Mathieu Chicard,Nadine Van Roy,Ales Vicha,Godelieve A.M. Tytgat,Nico Callewaert,Katleen De Preter,Bram De Wilde,Bram De Wilde +18 more
TL;DR: This work provides proof-of-concept of histopathologic classification of paediatric tumours using cell-free reduced representation bisulphite sequencing (cf-RRBS) from retrospectively collected plasma and cerebrospinal fluid samples and determines the correct tumour type in 49 out of 60 samples.
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microRNAs in colon cancer: a roadmap for discovery.
Simona Rossi,Antonio Fabio Di Narzo,Pieter Mestdagh,Bart Jacobs,F. Bosman,Bengt Gustavsson,Bernard Majoie,Arnaud Roth,Jo Vandesompele,Isidore Rigoutsos,Mauro Delorenzi,Mauro Delorenzi,Sabine Tejpar +12 more
TL;DR: This review intends to provide a road map in the jungle of publications of miRNA in colorectal cancer, focusing on data availability and new ways to generate biologically relevant information out of these huge amounts of data.
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Discovery and validation of a serum microRNA signature to characterize oligo- and polymetastatic prostate cancer: not ready for prime time
Bert Dhondt,Bert Dhondt,Elise De Bleser,Tom Claeys,Sarah Buelens,Nicolaas Lumen,Jo Vandesompele,Anneleen Beckers,Valérie Fonteyne,Kim Van der Eecken,Aurélie De Bruycker,Jérôme Paul,Pierre Gramme,Piet Ost +13 more
TL;DR: Although PC patients with oligometastatic disease had a more favorable prognosis, no serum-derived biomarkers allowing for prospective discrimination of oligo- and polymetastatic prostate cancer patients could be identified.
Journal Article
Predicting outcomes for children with neuroblastoma.
Joëlle Vermeulen,Katleen De Preter,Pieter Mestdagh,Genevieve Laureys,Franki Speleman,Jo Vandesompele +5 more
TL;DR: In this article, the authors proposed new prognostic markers, including copy number aberrations, gene expression signatures, and epigenetic markers, for improved risk estimation at the time of diagnosis and to improve the choice of risk related therapy.
Journal Article
Standardization of qPCR and RT-qPCR
TL;DR: Now that qPCR has come of age, standardization is needed to ensure its validity, prompting the recent formulation of guidelines to increase experimental transparency, promote consistency between laborato, and protect the integrity of the scientific literature.