J
Jo Vandesompele
Researcher at Ghent University
Publications - 406
Citations - 67052
Jo Vandesompele is an academic researcher from Ghent University. The author has contributed to research in topics: Neuroblastoma & microRNA. The author has an hindex of 88, co-authored 383 publications receiving 59368 citations. Previous affiliations of Jo Vandesompele include Washington University in St. Louis & Ghent University Hospital.
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Journal Article
Microrna signatures in genetic subtypes of t-cell acute lymphoblastic leukemia
Joni Van der Meulen,Pieter Van Vlierberghe,Pieter Mestdagh,Jo Vandesompele,Bruce Poppe,Nadine Van Roy,Tom Taghon,Jean Plum,Barbara Cauwelier,Dld Selleslag,P. Heimann,Peter Vandenberghe,Nicole Dastugue,Eric Delabesse,Carine Gervais,M.J. Gregoire,M J Mozziconacci,Christine Lefebvre,Jpp Meijerink,Jessica G.C.A.M. Buijs-Gladdines,Barbara De Moerloose,Yves Benoit,Anne De Paepe,Franki Speleman +23 more
TL;DR: In this article, the authors investigated whether different genetic subgroups in T-ALL are characterized by distinct miRNA expression patterns, i.e., consistently active, completely absent or temporally regulated during T-cell development.
Proceedings ArticleDOI
Abstract B49: Substantial performance differences among RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control study—important considerations for liquid biopsies
Anneleen Decock,Jasper Anckaert,Celine Everaert,Justine Nuytens,Scott Kuersten,An Hendrix,Jo Vandesompele,Pieter Mestdagh,Bert Dhondt,Ruben Van Paemel,Kimberly Verniers,Gary P. Schroth,Carolina Fierro,Nurten Yigit,Kathleen Schoofs,Annelien Morlion,Jill Deleu,Eva Hulstaert,Francisco Avila Cobos,Nele Nijs,Eveline Vanden Eynde,Hetty Helsmoortel,Olivier De Wever,Annouck Philippron +23 more
TL;DR: Decock et al. as discussed by the authors evaluated the impact of pre-analytical variables on downstream sequencing of blood-derived exRNAs using deep transcriptome profiling of all small and messenger RNAs from healthy donors' plasma.
Journal ArticleDOI
Genetisch geïnspireerde toekomstperspectieven voor de therapie van het neuroblastoom
Bram De Wilde,Tom Van Maerken,Katleen De Preter,Nadine Van Roy,Genevieve Laureys,Jo Vandesompele,Franki Speleman +6 more
TL;DR: De prognose is immers – ondanks zeer intensieve multimodale therapie – nog steeds ongunstig voor kinderen met een hoogrisicotumor die ouder dan achttien maanden zijn bij de diagnose.
Journal Article
ALK(F1174L) is a driving oncogene of neuroblastoma in transgenic mice
Johannes H. Schulte,Lukas C. Heukamp,Theresa Thor,Candy Kumps,Katleen De Preter,Bram De Wilde,Jo Vandesompele,Franki Speleman,Alexander Schramm,Angelika Eggert +9 more
CASP8 SNP D302H (rs1045485) is associated with worse survival in MYCN-amplified neuroblastoma patients
Ali Rihani,Bram De Wilde,Fjoralba Zeka,Genevieve Laureys,Nadine Francotte,Gian Paolo Tonini,Simona Coco,Rogier Versteeg,Rosa Noguera,Johannes H. Schulte,Angelika Eggert,Raymond L. Stallings,Franki Speleman,Jo Vandesompele,Tom Van Maerken +14 more
TL;DR: A missense SNP in exon 10 of the CASP8 gene SNP D302H was associated with worse overall and event-free survival in patients with MYCN-amplified neuroblastoma tumors.