J
Jo Vandesompele
Researcher at Ghent University
Publications - 406
Citations - 67052
Jo Vandesompele is an academic researcher from Ghent University. The author has contributed to research in topics: Neuroblastoma & microRNA. The author has an hindex of 88, co-authored 383 publications receiving 59368 citations. Previous affiliations of Jo Vandesompele include Washington University in St. Louis & Ghent University Hospital.
Papers
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regionsfor detection of mRNA expression imbalance Expression imbalance map: a new visualization
Michitaka Hirose,Hiroyuki Aburatani,Makoto Kano,Kunihiro Nishimura,Shumpei Ishikawa,Shuichi Tsutsumi,Katleen De Preter,Roland Barriot,Frank Speleman,Jo Vandesompele,Yves Moreau +10 more
Posted ContentDOI
The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival
Shanna Dewaele,Louis Delhaye,B. De Paepe,E. De Bony,J. De Wilde,Katrien Vanderheyden,Jasper Anckaert,Nurten Yigit,E. VandenEynde,Fariba Nemati,Didier Decaudin,Aart G. Jochemsen,Eleonora Leucci,Jo Vandesompele,J. Van Dorpe,Jean-Christophe Marine,R. Van Coster,Sven Eyckerman,Pieter Mestdagh +18 more
TL;DR: In this article, the authors investigated the therapeutic potential of SAMMSON inhibition in uveal melanoma (UM) cells and evaluated the impact of antisense oligonucleotide (ASO)-mediated SAMMSon inhibition in a panel of UM cell lines and patient derived xenograft (PDX) models.
Journal ArticleDOI
Blocking Abundant RNA Transcripts by High-Affinity Oligonucleotides during Transcriptome Library Preparation
Celine Everaert,Jasper Verwilt,Kimberly Verniers,Niels Vandamme,Alvaro Marcos Rubio,Jo Vandesompele,Pieter Mestdagh +6 more
TL;DR: In this article , an easy-to-use strategy based on high-affinity RNA-binding oligonucleotides was developed to block reverse transcription and PCR amplification of specific RNA transcripts, thereby substantially reducing their abundance in the final sequencing library.
Journal ArticleDOI
RNA Extraction Method Impacts Quality Metrics and Sequencing Results in Formalin-Fixed, Paraffin-Embedded Tissue Samples.
Philippe Decruyenaere,Kimberly Verniers,Franco Poma-Soto,J. Van Dorpe,Fritz Offner,Jo Vandesompele +5 more
TL;DR: In this paper , the impact of three different RNA extraction methods on yield, quality, and sequencing-based gene expression results in FFPE samples was compared in 16 patients with diffuse large B-cell lymphoma.
Posted ContentDOI
When DNA gets in the way in RNA-seq experiments, a sequel
Jasper Verwilt,María Dolores Giráldez,Wim Trypsteen,Ruben Van Paemel,Katleen De Preter,Pieter Mestdagh,Jo Vandesompele +6 more
TL;DR: To assess whether the newly data generated may suffer from DNA contamination, the publicly available sequencing data was downloaded and two quality control metrics were evaluated, which suggest the data and results presented by Yan et al. are affected by DNA contamination.