J
Jo Vandesompele
Researcher at Ghent University
Publications - 406
Citations - 67052
Jo Vandesompele is an academic researcher from Ghent University. The author has contributed to research in topics: Neuroblastoma & microRNA. The author has an hindex of 88, co-authored 383 publications receiving 59368 citations. Previous affiliations of Jo Vandesompele include Washington University in St. Louis & Ghent University Hospital.
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Journal ArticleDOI
Disclosing quantitative RT‐PCR raw data during manuscript submission: a call for action
Andreas Untergasser,Jan Hellemans,Michael W. Pfaffl,Jan M. Ruijter,Maurice J.B. van den Hoff,Mihnea P. Dragomir,Douglas Adamoski,Sandra Martha Gomes Dias,Rui L. Reis,Manuela Ferracin,Emmanuel Dias-Neto,Ian Marsh,Mikael Kubista,Muller Fabbri,Ajay Goel,Ondrej Slaby,Erik Knutsen,Baoqing Chen,Massimo Negrini,Koshi Mimori,Martin Pichler,Maria Papatriantafyllou,Simone Anfossi,Thomas D. Schmittgen,Jim F. Huggett,Stephen A. Bustin,Jo Vandesompele,George A. Calin +27 more
TL;DR: The Real-time PCR Data Essential Spreadsheet Format (RDES) as discussed by the authors was created for the purpose of supporting the verification of scientific data reproducibility in RNA profiling and sequencing studies.
Posted ContentDOI
Patient-specific alterations in blood plasma cfRNA profiles enable accurate classification of cancer patients and controls
Annelien Morlion,Philippe Decruyenaere,K. Schoofs,Jasper Anckaert,Justine Nuytens,E. Vanden Eynde,Kimberly Verniers,Celine Everaert,Fritz Offner,J. Van Dorpe,Jo Vandesompele,Pieter Mestdagh +11 more
TL;DR: In this paper , the authors applied mRNA capture sequencing of blood plasma cell-free RNA from 266 cancer patients and cancer-free controls (discovery n=208, 25 cancer types; validation n=58, 3 types).
Journal ArticleDOI
Longitudinal evaluation of serum microRNAs as biomarkers for neuroblastoma burden and therapeutic p53 reactivation
Alan Van Goethem,Jill Deleu,Nurten Yigit,Celine Everaert,Myrthala Moreno-Smith,Sanjeev A. Vasudevan,Fjoralba Zeka,Fleur Demuynck,Eveline Barbieri,Franki Speleman,Pieter Mestdagh,Jason M. Shohet,Jo Vandesompele,Tom Van Maerken +13 more
TL;DR: In this paper , the authors evaluated whether circulating miRNAs are suitable to monitor neuroblastoma tumour burden and whether treatment-induced changes of miRNA abundance in the tumour are detectable in serum.
Journal ArticleDOI
Comprehensive RNA dataset of tissue and plasma from patients with esophageal cancer or precursor lesions
K. Schoofs,Annouck Philippron,Francisco Avila Cobos,Jan Koster,Steve Lefever,Jasper Anckaert,Danny De Looze,Jo Vandesompele,Piet Pattyn,Katleen De Preter +9 more
TL;DR: In this paper , the authors performed comprehensive RNA (coding and non-coding) profiling in various samples from 17 patients diagnosed with esophageal adenocarcinoma, high-grade dysplastic or non-dysplastic Barrett's esophagus.
Posted ContentDOI
Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision
Marieke Vromman,Jasper Anckaert,Stefania Bortoluzzi,Alessia Buratin,Chia-Ying Chen,Qinjie Chu,Trees-Juen Chuang,Roozbeh Dehghannasiri,Christoph Dieterich,Xin Dong,Paul Flicek,Enrico Gaffo,Wanjun Gu,Chunjiang He,Steve Hoffmann,Osagie G. Izuogu,Michael S. Jackson,Tobias Jakobi,Eric C. Lai,Justine Nuytens,Julia Salzman,Mauro Santibanez-Koref,Peter F. Stadler,Olivier Thas,Eveline Vanden Eynde,Kimberly Verniers,Guoxia Wen,Jakub Orzechowski Westholm,Li Yang,Chuyu Ye,Nurten Yigit,Guoliang Yuan,Jinyang Zhang,Fangqing Zhao,Jo Vandesompele,Pieter-Jan Volders +35 more
TL;DR: In this paper , the authors set up a circRNA detection tool benchmarking study, in which 16 tools were used and detected over 315,000 unique circRNAs in three deeply sequenced human cell types.