J
Jon Clardy
Researcher at Harvard University
Publications - 990
Citations - 62414
Jon Clardy is an academic researcher from Harvard University. The author has contributed to research in topics: Absolute configuration & Bacteria. The author has an hindex of 116, co-authored 983 publications receiving 56617 citations. Previous affiliations of Jon Clardy include Howard Hughes Medical Institute & University of Chicago.
Papers
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Journal ArticleDOI
Neamphine, a sulfur containing aromatic heterocycle isolated from the marine sponge neamphius huxleyi
E. Dilip de Silva,Julie S. Racok,Raymond J. Andersen,Theresa M. Allen,Linda S. Brinen,Jon Clardy +5 more
TL;DR: The structure of neamphine (1), a cytotoxic metabolite of the marine sponge Neamphius huxleyi, has been solved by single crystal x-ray diffraction analysis, Neamphine represents the first example, either from nature or synthesis, of the imidazo[4,5]-1,2-thiazine ring system.
Journal ArticleDOI
Cytoskyrins A and B, New BIA Active Bisanthraquinones Isolated from an Endophytic Fungus.
TL;DR: The biochemical induction assay (BIA) is a rapid (colorimetric) bacterial assay used to identify compounds that damage DNA or inhibit DNA synthesis and thereby identify potential natural product anticancer agents.
Journal ArticleDOI
Rapid vinyl shifts in spiro[4.4]polyenes: verification of the rate-determining step and the identity of the migrating group
Patent
Antitumor compound, compositions and method of use
TL;DR: In this paper, a method for isolating same from a red alga, antitumor compositions containing same and methods of using same for treating patients with cancer were described. The compound of the present invention is 6(R)-bromo-3(S)-bronomethyl-7-methyl-2,3,7-trichloro-1-octene.