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Jon Clardy

Researcher at Harvard University

Publications -  990
Citations -  62414

Jon Clardy is an academic researcher from Harvard University. The author has contributed to research in topics: Absolute configuration & Bacteria. The author has an hindex of 116, co-authored 983 publications receiving 56617 citations. Previous affiliations of Jon Clardy include Howard Hughes Medical Institute & University of Chicago.

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Mammalian Cells Engineered To Produce New Steroids

TL;DR: A Rosetta docking model of CYP7B1 suggested that these substrates’ D‐ring hydroxy groups might prevent them from binding in the same way as the native substrates, bringing different carbon atoms close to the active ferryl oxygen atom.
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Bacteria regulate choanoflagellate development with lipid activators, inhibitors, and synergists

TL;DR: This study isolates and characterize bacterial molecules that regulate multicellular development in the closest living relatives of animals, the choanoflagellate, and finds that multiple bacterially-derived lipids converge to activate, enhance, and inhibit choan oflageLLate multICEllular development.