M
Mark E. McComb
Researcher at Boston University
Publications - 74
Citations - 4180
Mark E. McComb is an academic researcher from Boston University. The author has contributed to research in topics: Mass spectrometry & Sample preparation in mass spectrometry. The author has an hindex of 33, co-authored 74 publications receiving 3863 citations. Previous affiliations of Mark E. McComb include Boston University Medical Campus & University of Virginia.
Papers
More filters
Journal ArticleDOI
A common open representation of mass spectrometry data and its application to proteomics research
Patrick G. A. Pedrioli,Jimmy K. Eng,Robert Hubley,Mathijs Vogelzang,Eric W. Deutsch,Brian Raught,Brian S. Pratt,Erik Nilsson,Ruth Hogue Angeletti,Rolf Apweiler,Kei Cheung,Catherine E. Costello,Henning Hermjakob,Sequin Huang,Randall K. Julian,Eugene A. Kapp,Mark E. McComb,Stephen G. Oliver,Gilbert S. Omenn,Norman W. Paton,Richard J. Simpson,Richard D. Smith,Chris F. Taylor,Weimin Zhu,Ruedi Aebersold +24 more
TL;DR: The 'mzXML' format is introduced, an open, generic XML (extensible markup language) representation of MS data that will facilitate data management, interpretation and dissemination in proteomics research.
Journal ArticleDOI
Software Tool for Researching Annotations of Proteins: Open-Source Protein Annotation Software with Data Visualization
TL;DR: The Software Tool for Researching Annotations of Proteins (STRAP), a user-friendly, open-source C# application that automatically obtains gene ontology (GO) terms associated with proteins in a proteomics results ID list using the freely accessible UniProtKB and EBI GOA databases.
Journal ArticleDOI
The cytosolic entry of diphtheria toxin catalytic domain requires a host cell cytosolic translocation factor complex.
Ryan Ratts,Huiyan Zeng,Eric A. Berg,Clare Blue,Mark E. McComb,Cathy E. Costello,Johanna C. vanderSpek,John R. Murphy +7 more
TL;DR: Results presented here suggest a common and fundamental mechanism for C-domain translocation across early endosomal membranes and demonstrate that thioredoxin reductase activity plays an essential role in the cytosolic release of the C- domain.
Journal ArticleDOI
Isotope-coded affinity tag (ICAT) approach to redox proteomics: identification and quantitation of oxidant-sensitive cysteine thiols in complex protein mixtures.
Mahadevan Sethuraman,Mark E. McComb,Hua Huang,Sequin Huang,Tyler Heibeck,Catherine E. Costello,Richard A. Cohen +6 more
TL;DR: Of the many protein thiols labeled by the ICAT, only relatively few were oxidized more than 50% despite the high concentration of oxidant used, indicating that oxidant-sensitiveThiols are relatively rare, and denoting their specificity and potential functional relevance.
Journal ArticleDOI
Human Proteinpedia enables sharing of human protein data.
Suresh Mathivanan,Suresh Mathivanan,Mukhtar Ahmed,Natalie G. Ahn,Hainard Alexandre,Ramars Amanchy,Philip C. Andrews,Joel S. Bader,Brian M. Balgley,Marcus Bantscheff,Keiryn L. Bennett,Erik Björling,Blagoy Blagoev,Ron Bose,Samir K. Brahmachari,Alma S Burlingame,Xosé R. Bustelo,Gerard Cagney,Greg T. Cantin,Helene L. Cardasis,Julio E. Celis,Raghothama Chaerkady,Feixia Chu,Philip A. Cole,Catherine E. Costello,Robert J. Cotter,David K. Crockett,James P. DeLany,Angelo M. De Marzo,Leroi V. DeSouza,Eric W. Deutsch,E. Dransfield,Gerard Drewes,Arnaud Droit,Michael J. Dunn,Kojo S.J. Elenitoba-Johnson,Rob M. Ewing,Jennifer E. Van Eyk,Vitor M. Faça,Jayson A. Falkner,Xiangming Fang,Catherine Fenselau,Daniel Figeys,Pierre Gagné,Cecilia Gelfi,Kris Gevaert,Jeffrey M. Gimble,Florian Gnad,Renu Goel,Pavel Gromov,Samir M. Hanash,William S. Hancock,H. C. Harsha,Gerald W. Hart,Faith A. Hays,Fuchu He,Prashantha Hebbar,Kenny Helsens,Heiko Hermeking,Winston Hide,Karin Hjernø,Denis F. Hochstrasser,Oliver Hofmann,David M Horn,Ralph H. Hruban,Nieves Ibarrola,Peter James,Ole N. Jensen,Pia Hønnerup Jensen,Peter Jung,Kumaran Kandasamy,Kumaran Kandasamy,Indu Kheterpal,Reiko F. Kikuno,Ulrike Korf,Roman Körner,Bernhard Kuster,Min-Seok Kwon,Hyoung Joo Lee,Young Jin Lee,Michael Lefevre,Minna Lehvaslaiho,Pierre Lescuyer,Fredrik Levander,Megan S. Lim,Christian Löbke,Joseph A. Loo,Matthias Mann,Matthias Mann,Lennart Martens,Juan Martínez-Heredia,Mark E. McComb,James P. McRedmond,Alexander Mehrle,Rajasree Menon,Christine A. Miller,Harald Mischak,Subburaman Mohan,Riaz Mohmood,Henrik Molina,Michael Moran,James D. Morgan,Robert Moritz,Martine Morzel,David C. Muddiman,Anuradha Nalli,J. Daniel Navarro,Thomas A. Neubert,Osamu Ohara,Rafael Oliva,Gilbert S. Omenn,Masaaki Oyama,Young Ki Paik,Kyla Pennington,Rainer Pepperkok,Balamurugan Periaswamy,Balamurugan Periaswamy,Emanuel F. Petricoin,Guy G. Poirier,T. S. Keshava Prasad,Samuel O. Purvine,B. Abdul Rahiman,Prasanna Ramachandran,Y. L. Ramachandra,Robert H. Rice,Jens Rick,Ragna Rönnholm,Johanna Salonen,Jean-Charles Sanchez,Thierry Sayd,Beerelli Seshi,Kripa Shankari,Shi Jun Sheng,Vivekananda Shetty,K. Shivakumar,Richard J. Simpson,Ravi Sirdeshmukh,K. W. Michael Siu,Jeffrey C. Smith,Richard D. Smith,David J. States,Sumio Sugano,Matthew J. Sullivan,Giulio Superti-Furga,Maarit Takatalo,Visith Thongboonkerd,Jonathan C. Trinidad,Mathias Uhlén,Joël Vandekerckhove,Julian Vasilescu,Timothy D. Veenstra,Jose-Manuel Vidal-Taboada,Mauno Vihinen,Robin Wait,Xiaoyue Wang,Stefan Wiemann,Billy Wu,Tao Xu,John R. Yates,Jun Zhong,Ming Zhou,Yunping Zhu,Petra Zürbig,Akhilesh Pandey +163 more
TL;DR: MMCD is a practical tool for expediting the time-consuming steps of identifying and researching small molecules and is compatible with both NMR and MS data and facilitates high-throughput metabolomics investigations.