J
Jayson A. Falkner
Researcher at University of Michigan
Publications - 11
Citations - 851
Jayson A. Falkner is an academic researcher from University of Michigan. The author has contributed to research in topics: Peptide spectral library & Mass spectrometry data format. The author has an hindex of 10, co-authored 11 publications receiving 813 citations. Previous affiliations of Jayson A. Falkner include University of Colorado Boulder.
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Journal ArticleDOI
A HUPO test sample study reveals common problems in mass spectrometry–based proteomics
Alexander W. Bell,Eric W. Deutsch,Catherine E. Au,Robert E. Kearney,Ron Beavis,Salvatore Sechi,Tommy Nilsson,John J.M. Bergeron,Thomas A. Beardslee,Thomas Chappell,Gavin Meredith,Peter J. Sheffield,Phillip Gray,Mahbod Hajivandi,Marshall Pope,Paul F. Predki,Majlinda Kullolli,Marina Hincapie,William S. Hancock,Wei Jia,Lina Song,Lei Li,Junying Wei,Bing Yang,Jinglan Wang,Wantao Ying,Yangjun Zhang,Yun Cai,Xiaohong Qian,Fuchu He,Helmut E. Meyer,Christian Stephan,Martin Eisenacher,Katrin Marcus,Elmar Langenfeld,Caroline May,Steve A. Carr,Rushdy Ahmad,Wenhong Zhu,Jeffrey W. Smith,Samir M. Hanash,Jason J. Struthers,Hong Wang,Qing Zhang,Yanming An,Radoslav Goldman,Elisabet Carlsohn,Sjoerd van der Post,Kenneth E. Hung,David A. Sarracino,Kenneth C. Parker,Bryan Krastins,Raju Kucherlapati,Sylvie Bourassa,Guy G. Poirier,Eugene A. Kapp,Heather Patsiouras,Robert L. Moritz,Richard J. Simpson,Benoit Houle,Sylvie Laboissiere,Pavel Metalnikov,Vivian Nguyen,Tony Pawson,Catherine C. L. Wong,Daniel Cociorva,John R. Yates,Michael J. Ellison,Ana Lopez-Campistrous,P. D. Semchuk,Yueju Wang,Peipei Ping,Giuliano Elia,Michael J. Dunn,Kieran Wynne,Angela K. Walker,John R. Strahler,Philip C. Andrews,Brian L. Hood,William L. Bigbee,Thomas P. Conrads,Derek Smith,Christoph H. Borchers,Gilles A. Lajoie,Sean C. Bendall,Kaye D. Speicher,David W. Speicher,Masanori Fujimoto,Kazuyuki Nakamura,Young Ki Paik,Sang Yun Cho,Min-Seok Kwon,Hyoung Joo Lee,Seul Ki Jeong,An Sung Chung,Christine A. Miller,Rudolf Grimm,Katy Williams,Craig A. Dorschel,Jayson A. Falkner,Lennart Martens,Juan Antonio Vizcaíno +101 more
TL;DR: Central analysis determined missed identifications, environmental contamination, database matching and curation of protein identifications as sources of problems in liquid chromatography–mass spectrometry–based proteomics.
Journal ArticleDOI
Human Proteinpedia enables sharing of human protein data.
Suresh Mathivanan,Suresh Mathivanan,Mukhtar Ahmed,Natalie G. Ahn,Hainard Alexandre,Ramars Amanchy,Philip C. Andrews,Joel S. Bader,Brian M. Balgley,Marcus Bantscheff,Keiryn L. Bennett,Erik Björling,Blagoy Blagoev,Ron Bose,Samir K. Brahmachari,Alma S Burlingame,Xosé R. Bustelo,Gerard Cagney,Greg T. Cantin,Helene L. Cardasis,Julio E. Celis,Raghothama Chaerkady,Feixia Chu,Philip A. Cole,Catherine E. Costello,Robert J. Cotter,David K. Crockett,James P. DeLany,Angelo M. De Marzo,Leroi V. DeSouza,Eric W. Deutsch,E. Dransfield,Gerard Drewes,Arnaud Droit,Michael J. Dunn,Kojo S.J. Elenitoba-Johnson,Rob M. Ewing,Jennifer E. Van Eyk,Vitor M. Faça,Jayson A. Falkner,Xiangming Fang,Catherine Fenselau,Daniel Figeys,Pierre Gagné,Cecilia Gelfi,Kris Gevaert,Jeffrey M. Gimble,Florian Gnad,Renu Goel,Pavel Gromov,Samir M. Hanash,William S. Hancock,H. C. Harsha,Gerald W. Hart,Faith A. Hays,Fuchu He,Prashantha Hebbar,Kenny Helsens,Heiko Hermeking,Winston Hide,Karin Hjernø,Denis F. Hochstrasser,Oliver Hofmann,David M Horn,Ralph H. Hruban,Nieves Ibarrola,Peter James,Ole N. Jensen,Pia Hønnerup Jensen,Peter Jung,Kumaran Kandasamy,Kumaran Kandasamy,Indu Kheterpal,Reiko F. Kikuno,Ulrike Korf,Roman Körner,Bernhard Kuster,Min-Seok Kwon,Hyoung Joo Lee,Young Jin Lee,Michael Lefevre,Minna Lehvaslaiho,Pierre Lescuyer,Fredrik Levander,Megan S. Lim,Christian Löbke,Joseph A. Loo,Matthias Mann,Matthias Mann,Lennart Martens,Juan Martínez-Heredia,Mark E. McComb,James P. McRedmond,Alexander Mehrle,Rajasree Menon,Christine A. Miller,Harald Mischak,Subburaman Mohan,Riaz Mohmood,Henrik Molina,Michael Moran,James D. Morgan,Robert Moritz,Martine Morzel,David C. Muddiman,Anuradha Nalli,J. Daniel Navarro,Thomas A. Neubert,Osamu Ohara,Rafael Oliva,Gilbert S. Omenn,Masaaki Oyama,Young Ki Paik,Kyla Pennington,Rainer Pepperkok,Balamurugan Periaswamy,Balamurugan Periaswamy,Emanuel F. Petricoin,Guy G. Poirier,T. S. Keshava Prasad,Samuel O. Purvine,B. Abdul Rahiman,Prasanna Ramachandran,Y. L. Ramachandra,Robert H. Rice,Jens Rick,Ragna Rönnholm,Johanna Salonen,Jean-Charles Sanchez,Thierry Sayd,Beerelli Seshi,Kripa Shankari,Shi Jun Sheng,Vivekananda Shetty,K. Shivakumar,Richard J. Simpson,Ravi Sirdeshmukh,K. W. Michael Siu,Jeffrey C. Smith,Richard D. Smith,David J. States,Sumio Sugano,Matthew J. Sullivan,Giulio Superti-Furga,Maarit Takatalo,Visith Thongboonkerd,Jonathan C. Trinidad,Mathias Uhlén,Joël Vandekerckhove,Julian Vasilescu,Timothy D. Veenstra,Jose-Manuel Vidal-Taboada,Mauno Vihinen,Robin Wait,Xiaoyue Wang,Stefan Wiemann,Billy Wu,Tao Xu,John R. Yates,Jun Zhong,Ming Zhou,Yunping Zhu,Petra Zürbig,Akhilesh Pandey +163 more
TL;DR: MMCD is a practical tool for expediting the time-consuming steps of identifying and researching small molecules and is compatible with both NMR and MS data and facilitates high-throughput metabolomics investigations.
Journal ArticleDOI
A Spectral Clustering Approach to MS/MS Identification of Post-Translational Modifications
TL;DR: A novel algorithm is described, "Bonanza", for clustering spectra without knowledge of peptide or protein identifications, which significantly more spectra can be identified with this approach, including spectra with unexpected potential modifications or amino-acid substitutions.
Journal ArticleDOI
Rapid optimization of MRM-MS instrument parameters by subtle alteration of precursor and product m/z targets.
Carly A. Sherwood,Ashley Eastham,Lik Wee Lee,Jenni Risler,Hamid Mirzaei,Jayson A. Falkner,Daniel Martin +6 more
TL;DR: A workflow functional on both Waters Quattro Premier and ABI 4000 QTRAP triple quadrupole instruments that allows rapid determination of the optimal value of any programmable instrument parameter for each MRM transition is devised.
Journal ArticleDOI
Exploring protein-ligand recognition with Binding MOAD.
Richard D. Smith,Liegi Hu,Jayson A. Falkner,Mark L. Benson,Jason P. Nerothin,Heather A. Carlson +5 more
TL;DR: It is determined that most cavities and ligands are well buried in the complexes of Binding MOAD, which fits with the common paradigm that a large degree of contact between the ligand and protein is significant in molecular recognition.