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Shahzad Ahmad

Researcher at Erasmus University Rotterdam

Publications -  44
Citations -  2753

Shahzad Ahmad is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Genome-wide association study & Medicine. The author has an hindex of 14, co-authored 32 publications receiving 1351 citations. Previous affiliations of Shahzad Ahmad include German Cancer Research Center & Erasmus University Medical Center.

Papers
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Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Rebecca Sims, +487 more
- 01 Sep 2017 - 
TL;DR: Three new genome-wide significant nonsynonymous variants associated with Alzheimer's disease are observed, providing additional evidence that the microglia-mediated innate immune response contributes directly to the development of Alzheimer's Disease.
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New insights into the genetic etiology of Alzheimer’s disease and related dementias

Céline Bellenguez, +401 more
- 01 Apr 2022 - 
TL;DR: This paper performed a two-stage genome-wide association study with 111,326 clinically diagnosed/proxy AD cases and 677,663 controls and found 75 risk loci, of which 42 were new at the time of analysis.
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Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome.

Siamak Mahmoudiandehkordi, +36 more
- 01 Jan 2019 - 
TL;DR: This data indicates that BAs, products of cholesterol metabolism and clearance, are produced in the liver and are further metabolized by gut bacteria and seem dysregulated in Alzheimer's disease (AD).
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Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

Joshua C. Bis, +118 more
- 01 Aug 2020 - 
TL;DR: The Alzheimer’s Disease Sequencing Project undertook whole exome sequencing in 5,740 late-onset Alzheimer disease cases and 5,096 cognitively normal controls primarily of European ancestry, identifying novel and predicted functional genetic variants in genes previously associated with AD.
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Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers.

Kwangsik Nho, +20 more
- 01 Feb 2019 - 
TL;DR: In this paper, the association of BAs with the "A/T/N" (amyloid, tau, and neurodegeneration) biomarkers for AD: cerebrospinal fluid (CSF), atrophy (magnetic resonance imaging), and brain glucose metabolism (FDG PET).