M
Mark A. van Buchem
Researcher at Leiden University
Publications - 69
Citations - 9696
Mark A. van Buchem is an academic researcher from Leiden University. The author has contributed to research in topics: Hyperintensity & Population. The author has an hindex of 37, co-authored 69 publications receiving 7671 citations. Previous affiliations of Mark A. van Buchem include Leiden University Medical Center.
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Journal ArticleDOI
Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration
Joanna M. Wardlaw,Eric E. Smith,Geert J. Biessels,Charlotte Cordonnier,Franz Fazekas,Richard Frayne,Richard I. Lindley,John T. O'Brien,Frederik Barkhof,Oscar R. Benavente,Sandra E. Black,Carol Brayne,Monique M.B. Breteler,Hugues Chabriat,Charles DeCarli,Frank-Erik de Leeuw,Fergus N. Doubal,Marco Duering,Nick C. Fox,Steven M. Greenberg,Vladimir Hachinski,Ingo Kilimann,Vincent Mok,Robert J. van Oostenbrugge,Leonardo Pantoni,Oliver Speck,Blossom C. M. Stephan,Stefan J. Teipel,Anand Viswanathan,David J. Werring,Christopher Chen,Colin Smith,Mark A. van Buchem,Bo Norrving,Philip B. Gorelick,Martin Dichgans +35 more
TL;DR: This Position Paper summarises the main outcomes of this international effort to provide the STandards for ReportIng Vascular changes on nEuroimaging (STRIVE).
Journal ArticleDOI
Whole brain resting-state analysis reveals decreased functional connectivity in major depression
Ilya M. Veer,Ilya M. Veer,Christian F. Beckmann,Christian F. Beckmann,Marie-José van Tol,Marie-José van Tol,Luca Ferrarini,Julien Milles,Dick J. Veltman,André Aleman,Mark A. van Buchem,Mark A. van Buchem,Nic J.A. van der Wee,Nic J.A. van der Wee,Serge A.R.B. Rombouts,Serge A.R.B. Rombouts +15 more
TL;DR: In this paper, the authors investigated whole-brain functional connectivity, unbiased by a priori definition of regions or networks of interest, in medication-free depressive patients without comorbidity.
Journal ArticleDOI
Vascular dysfunction-The disregarded partner of Alzheimer's disease
Melanie D. Sweeney,Axel Montagne,Abhay P. Sagare,Daniel A. Nation,Lon S. Schneider,Helena C. Chui,Michael G. Harrington,Judy Pa,Meng Law,Danny J.J. Wang,Russell E. Jacobs,Fergus N. Doubal,Joel Ramirez,Sandra E. Black,Helene Benveniste,Martin Dichgans,Costantino Iadecola,Seth Love,Philip M.W. Bath,Philip M.W. Bath,Hugh S. Markus,Rustam Al-Shahi Salman,Stuart M. Allan,Terence J. Quinn,Rajesh N. Kalaria,David J. Werring,Roxana O. Carare,Rhian M. Touyz,Steve C.R. Williams,Michael A. Moskowitz,Zvonimir S. Katusic,Sarah E. Lutz,Orly Lazarov,Richard D. Minshall,Jalees Rehman,Thomas P. Davis,Cheryl L. Wellington,Hector M. González,Chun Yuan,Samuel N. Lockhart,Timothy M. Hughes,Christopher Chen,Perminder S. Sachdev,John T. O'Brien,Ingmar Skoog,Leonardo Pantoni,Deborah Gustafson,Geert Jan Biessels,Anders Wallin,Eric E. Smith,Vincent Mok,Adrian Wong,Peter Passmore,Frederick Barkof,Frederick Barkof,Majon Muller,Monique M.B. Breteler,Monique M.B. Breteler,Gustavo C. Román,Edith Hamel,Sudha Seshadri,Sudha Seshadri,Rebecca F. Gottesman,Mark A. van Buchem,Zoe Arvanitakis,Julie A. Schneider,Lester R. Drewes,Vladimir Hachinski,Caleb E. Finch,Arthur W. Toga,Joanna M. Wardlaw,Berislav V. Zlokovic +71 more
TL;DR: Vascular imaging biomarkers of small vessel disease of the brain, which is responsible for >50% of dementia worldwide, including AD, are already established, well characterized, and easy to recognize and should be incorporated into the AD Research Framework to gain a better understanding of AD pathophysiology and aid in treatment efforts.
Journal ArticleDOI
Blood-Brain Barrier Leakage in Patients with Early Alzheimer Disease
Harm J. van de Haar,Saartje Burgmans,Jacobus F.A. Jansen,Matthias J.P. van Osch,Mark A. van Buchem,Majon Muller,Paul A. M. Hofman,Frans R.J. Verhey,Walter H. Backes +8 more
TL;DR: The results of this study showed global BBB leakage in patients with early AD that is associated with cognitive decline that may be part of a cascade of pathologic events that eventually lead to cognitive decline and dementia.
Journal ArticleDOI
Regional brain volume in depression and anxiety disorders.
Marie-José van Tol,Nic J.A. van der Wee,Odile A. van den Heuvel,M. Nielen,Liliana Ramona Demenescu,André Aleman,Remco J. Renken,Mark A. van Buchem,Frans G. Zitman,Dick J. Veltman +9 more
TL;DR: These findings indicate that reduced volume of the rostral-dorsal anterior cingulate gyrus is a generic effect in depression and anxiety disorders, independent of illness severity, medication use, and sex.