M
Mark P. Mattson
Researcher at Johns Hopkins University School of Medicine
Publications - 988
Citations - 151506
Mark P. Mattson is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Glutamate receptor & Neuroprotection. The author has an hindex of 200, co-authored 980 publications receiving 138033 citations. Previous affiliations of Mark P. Mattson include University of Kentucky & National Institutes of Health.
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Enhancing the GLP-1 receptor signaling pathway leads to proliferation and neuroprotection in human neuroblastoma cells
TL;DR: In this paper, the GLP-1 receptor was over-expressed on human neuroblastoma SH-SY5Y cells to generate a neuronal culture system featuring enhanced GLP1R signaling.
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Involvement of notch signaling in wound healing.
Srinivasulu Chigurupati,Thiruma V. Arumugam,Thiruma V. Arumugam,Tae Gen Son,Justin D. Lathia,Shafaq Jameel,Mohamed R. Mughal,Sung-Chun Tang,Dong-Gyu Jo,Dong-Gyu Jo,Simonetta Camandola,Marialuisa Giunta,Irina Rakova,Nazli B. McDonnell,Lucio Miele,Mark P. Mattson,Mark P. Mattson,Suresh Poosala +17 more
TL;DR: It is suggested that Notch signaling plays important roles in wound healing and tissue repair, and that targeting the Notch pathway might provide a novel strategy for treatment of wounds and for modulation of angiogenesis in other pathological conditions.
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Gene-diet interactions in brain aging and neurodegenerative disorders.
TL;DR: A prospective study of a large cohort of people in New York City revealed that those with low-calorie or low-fat diets had significantly lower risks for Alzheimer disease and Parkinson disease than did those with higher calorie intake, and the risks were more strongly correlated with calorie intake than with weight or body mass index.
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Exposure to polychlorinated biphenyls causes endothelial cell dysfunction
Michal Toborek,Steven W. Barger,Mark P. Mattson,Parvaneh Espandiari,Larry W. Robertson,Bernhard Hennig +5 more
TL;DR: It is suggested that certain PCBs may play a role in the development of atherosclerosis by causing endothelial cell dysfunction and a decrease in the barrier function of the vascular endothelium.
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Patterns of laminins and integrins in the embryonic ventricular zone of the CNS
Justin D. Lathia,Justin D. Lathia,Bruce L. Patton,D. Mark Eckley,Tim Magnus,Mohamed R. Mughal,Takako Sasaki,Maeve A. Caldwell,Mahendra S. Rao,Mahendra S. Rao,Mark P. Mattson,Charles ffrench-Constant +11 more
TL;DR: A significant role in the regulation of NSC fate for laminin/integrin signaling within the microenvironment of the VZ is suggested and a framework for future molecular and cellular analyses of the role of the ECM in neural development is provided.