Monica Milla

TL;DR: A meta-analysis of six ulcerative colitis genome-wide association study datasets found many candidate genes that provide potentially important insights into disease pathogenesis, including IL1R2, IL8RA-IL8RB, IL7R, IL12B, DAP, PRDM1, JAK2, IRF5, GNA12 and LSP1.

TL;DR: Whether an East–West gradient in the incidence of inflammatory bowel disease in Europe exists is investigated to find out whether international guidelines for diagnosis and initial treatment are not being followed uniformly by physicians.

TL;DR: Active IBD, old age and comorbidities were associated with a negative COVID-19 outcome, whereas IBD treatments were not, and Preventing acute IBD flares may avoid fatal CO VID-19 in patients with IBD.

TL;DR: The data examined in this meta-analysis do not support the use of diets as primary treatment for acute exacerbations of Crohn's disease in adults.

TL;DR: The results indicate that 5-ASA given daily by oral route and intermittently by topical route can be more effective than oral therapy alone and this form of combination treatment can be appropriate for patients at high risk of relapse.