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Nicholas A. Peppas
Researcher at University of Texas at Austin
Publications - 840
Citations - 101193
Nicholas A. Peppas is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Self-healing hydrogels & Polymer. The author has an hindex of 141, co-authored 825 publications receiving 90533 citations. Previous affiliations of Nicholas A. Peppas include National Technical University & University of Texas System.
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Biodegradable hydrophilic carriers for the oral delivery of hematological factor IX for hemophilia B treatment.
TL;DR: Evaluating the drug delivery application of this degradable P(MAA-g-EG) system, factor IX release studies showed site-specific release, and in vitro transport studies resulted in improved factor IX absorption, which significantly improved the delivery potential as compared to previously reported non-degradable drug delivery systems.
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Quantifying Tight Junction Disruption Caused by Biomimetic pH-Sensitive Hydrogel Drug Carriers.
TL;DR: A confocal microscopy imaging method was developed to determine the effect of microparticulate poly(methacrylic acid) grafted poly(ethylene glycol) (P(MAA-g-EG) hydrogel drug carriers on the integrity of claudin-1 and E-cadherin networks in Caco-2 monolayers.
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Friedel-Crafts crosslinking methods for polystyrene modification: 5. Sulfonated crosslinked polystyrene particles
TL;DR: In this paper, a new method of preparation of sulfonated, crosslinked polystyrene particles is described, which is formed by Friedel-Crafts suspension crosslinking of poly styrene dissolved in nitrobenzene.
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Effect of network mesh size and swelling to the drug delivery from pH responsive hydrogels
Rachel A. Hegab,Sibile Pardue,Xinggui Shen,Christopher G. Kevil,Nicholas A. Peppas,Mary Caldorera-Moore +5 more
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The use of x-ray photoelectron spectroscopy for the analysis of the surface of biomaterials
TL;DR: The interaction of a biomaterial with its environment occurs primarily at the material /biological fluid interface as discussed by the authors, but many interactions are specific to the surface region (wetting, adhesion, many catalytic reactions, blood compatibility, etc.).