N
Nicholas A. Peppas
Researcher at University of Texas at Austin
Publications - 840
Citations - 101193
Nicholas A. Peppas is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Self-healing hydrogels & Polymer. The author has an hindex of 141, co-authored 825 publications receiving 90533 citations. Previous affiliations of Nicholas A. Peppas include National Technical University & University of Texas System.
Papers
More filters
Journal ArticleDOI
Novel poly(ethylene glycol)-grafted, cationic hydrogels: Preparation, characterization and diffusive properties
TL;DR: In this paper, a new class of poly(ethylene glycol)-grafted, cationic hydrogels was prepared by copolymerization and simultaneous crosslinking of diethylaminoethyl methacrylate (DEAEM) and poly (ethylene gels) monomethacrylated (PEGMA), which exhibited a strong swelling ratio dependence on pH.
Journal ArticleDOI
Enzymatic Biodegradation of Hydrogels for Protein Delivery Targeted to the Small Intestine
TL;DR: Multiresponsive poly(methacrylic acid-co-N-vinylpyrrolidone) hydrogels were synthesized with biodegradable oligopeptide crosslinks and demonstrated pH-dependent loading of the protein insulin for oral delivery to the small intestine and enzyme-catalyzed degradation targeted by trypsin.
Journal ArticleDOI
Morphology of poly(methacrylic acid)/poly(N-isopropyl acrylamide) interpenetrating polymeric networks
Jing Zhang,Nicholas A. Peppas +1 more
TL;DR: The results showed that the porous size in the IPN was strongly influenced by the environmental pH and temperature, and decrease in pH and increase in temperature resulted in significant pore size decrease for the swollen IPNs hydrogels.
Journal ArticleDOI
Bioadhesive analysis of controlled-release systems. IV. An experimental method for testing the adhesion of microparticles with mucus
TL;DR: In this article, a method for testing and classifying the bioadhesive behavior of polymeric microparticles with or without drugs is presented, which is used to determine the adhesive forces between solid polymeric micro-microparticles of diameter up to 200 μm in contact with natural mucosa or with a mucin gel.
Journal ArticleDOI
Molecular Aspects of Mucoadhesive Carrier Development for Drug Delivery and Improved Absorption
TL;DR: The theoretical framework for achieving mucoadhesive systems as related to biomaterials science and the structure of the biomaterialS used is discussed.