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Patrick R. Hof
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 834
Citations - 73115
Patrick R. Hof is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Neocortex & Alzheimer's disease. The author has an hindex of 130, co-authored 796 publications receiving 64987 citations. Previous affiliations of Patrick R. Hof include Albert Einstein College of Medicine & National Institutes of Health.
Papers
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Journal ArticleDOI
Neurochemical and Structural Organization of the Principal Nucleus of the Inferior Olive in the Human
TL;DR: There was individual variability in the numbers and density of stained neurons in the human IOpr; such variability was not seen in other brainstem nuclei; these data are consistent with, and complement, earlier studies showing a dramatic age‐related increase in lipofuscin and decrease in RNA in thehuman IOpr.
Journal ArticleDOI
Vasoactive intestinal peptide as a mediator of intercellular communication in the cerebral cortex. Release, receptors, actions, and interactions with norepinephrine.
Pierre J. Magistretti,Monika M. Dietl,Patrick R. Hof,Jean-Luc Martin,José M. Palacios,Nicolas C. Schaad,Michel Schorderet +6 more
TL;DR: "This research is supported by Fonds National Suisse de la Recherche Scientifique Grants N" 3.357-0.86 and 3.969- 0.84.
Journal ArticleDOI
Supramodal Mechanisms of the Cognitive Control Network in Uncertainty Processing
TL;DR: The results suggest that the CCN implements cognitive control by processing uncertainty as abstract information independent of stimulus modality.
Journal ArticleDOI
Molecules, Mechanisms, and Disorders of Self-Domestication: Keys for Understanding Emotional and Social Communication from an Evolutionary Perspective.
TL;DR: The neural crest hypothesis as discussed by the authors states that the phenotypic features of the domestication syndrome are due to a reduced number or disruption of neural crest cells (NCCs) migration, as these cells differentiate at their final destinations and proliferate into different tissues whose activity is reduced by domestication.
Book ChapterDOI
Age-Related Morphologic Alterations in the Brain of Old World and New World Anthropoid Monkeys
Patrick R. Hof,Hulling Duan +1 more
TL;DR: It is shown that subtle alterations involving the neuropil as well as restricted domains of the dendritic trees are likely to contribute massively, together with molecular changes in specific neurotransmitter receptor proteins, to the cognitive and memory deficits observed in aged anthropoid monkeys.