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Patrick R. Hof
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 834
Citations - 73115
Patrick R. Hof is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Neocortex & Alzheimer's disease. The author has an hindex of 130, co-authored 796 publications receiving 64987 citations. Previous affiliations of Patrick R. Hof include Albert Einstein College of Medicine & National Institutes of Health.
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Journal ArticleDOI
Presenilin transgenic mice as models of Alzheimer's disease.
Gregory A. Elder,Gregory A. Elder,Miguel A. Gama Sosa,Miguel A. Gama Sosa,Rita De Gasperi,Rita De Gasperi,Dara L. Dickstein,Patrick R. Hof +7 more
TL;DR: Mice in which PS1 has been conditionally knocked out in adult forebrain on a PS2 null background develop a striking neurodegeneration that mimics AD neuropathology in being associated with neuronal and synaptic loss, astrogliosis and hyperphosphorylation of tau, although it is not accompanied by plaque deposits.
Journal ArticleDOI
Hemispheric asymmetry, modular variability and age-related changes in the human entorhinal cortex.
Goran Šimić,Sadi Bexheti,Zlatko Kelović,Marina Kos,Kristina Grbić,Patrick R. Hof,Ivica Kostović +6 more
TL;DR: The present data confirm the occurrence of age-related neuron loss in the entorhinal cortex and speculate that functional lateralization of the human entorHinal cortex may be associated with specialization for memory processing related to language.
Journal ArticleDOI
Parvalbumin in the monkey striate cortex: a quantitative immunoelectron-microscopy study.
TL;DR: It is observed that the vast majority of parvalbumin-immunoreactive synaptic contacts in the primary visual cortex of Macaca fascicularis are of the symmetric type, and these neurons are known to be inhibitory and to form symmetric synapses.
25th Annual Computational Neuroscience Meeting: CNS-2016
Tatyana O. Sharpee,Alain Destexhe,Mitsuo Kawato,Vladisla Sekulić,Frances K. Skinner,Daniel K. Wójcik,Chaitanya Chintaluri,Dorottya Cserpán,Zoltán Somogyvári,Jae Kyoung Kim,Zachary P. Kilpatrick,Matthew R. Bennett,Krešimir Josić,Irene Elices,David Arroyo,Rafael Levi,Francisco B. Rodriguez,Pablo Varona,Eunjin Hwang,Bowon Kim,Hio-Been Han,Tae Kim,James T. McKenna,Ritchie E. Brown,Robert W. McCarley,Jee Hyun Choi,James Rankin,Pamela Osborn Popp,John Rinzel,Alejandro Tabas,André Rupp,Emili Balaguer‑Ballester,Matias I. Maturana,David B. Grayden,Shaun L. Cloherty,Tatiana Kameneva,Michael R. Ibbotson,Hamish Meffin,Veronika Koren,Timm Lochmann,Valentin Dragoi,Klaus Obermayer,Maria Psarrou,Maria J. Schilstra,Neil Davey,Huiwen Ju,Michael L. Hines,Liang Chen,Jimin Kim,Will Leahy,Eli Shlizerman,Justas Birgolias,Richard C. Gerkin,Sharon M. Crook,Atthaphon Viriyopase,Raol-Martin Memmeshei,Yuri Dabaghian,Justin DeVuti,Luca Perotti,Ammo J. Kim,Lisa M. Fenk,Cheng Lyu,Gabby Malmon,Chang Zhao,Yves F. Widmer,Simon G. Sprecher,Geir Halnes,Maki-Martun Tuomo,Daniel Keller,Klas H. Petterson,Ole A. Andreassen,Gaute T. Elnevoll,Yasnori Yamada,Moira L. Steyn-Ross,D. Alistair Steyn-Ross,Jorge F. Meijas,John D. Murray,Henry Kennedy,Alexandra Kruscha,Jan Grewe,Benjamin Lidner,Laurent Badel,Ohta Kasumi,Yoshiko Tsuchimoto,Hokto Kazama,B. Kahng,Nicoladie D. Tam,Luca Pollonini,George Zouridakis,Jaehyun Soh,Dae Eun Kim,Minsu Yoo,Stephanie E. Palmer,Viviana Culmone,Ingo Bojak,Andrea Ferrario,Robert Merriosn-Hort,Roman Borisyuk,Chang Sub Kim,Taro Tezuka,Pangyu Joo,Rho Young-Ah,Shawn D. Burton,G. Bard,Petr Marsalek,Hoon-Hee Kim,Seok-hun Moon,Do-won Lee,Yaroslav I. Molkov,Khaldoun C. Hamade,Wondimu Teka,William H. Barnett,Taegyo Kim,Sergey N. Markin,Ilya A. Rybak,Csaba Forrow,Harald Demutz,László Demkó,Janos Vörös,Andrey Babichev,Haiping Huang,Christoph Metzner,Achim Schwikard,Bartosz Zurowski,James P. Roach,Leonard M. Sander,Michal Zochowski,Quinton M. Skilling,Nicolette Ognjanovski,Sara J. Aton,Michal Zochowski,Sheng-Ju Wang,Guang Ouyang,Mingsha Zhang,Michael Wong,Changsong Zhou,Peter A. Robinson,Paula Sanz-Leon,P.M. Drysdale,Felix Fung,Romesh G. Abeysuriya,Chris J. Rennle,X. Zhao,Yoonsuck Choe,Huei-Fang Yang,Yuanyuan Mi,Xiahoan Lin,Si Wu,Joscha Liedtke,Manual Schottdorf,Fred Wolf,Yorkio Yamamura,Jeffery R. Wickens,Timothy Rumbell,Julia Ramsey,Amy Reyes,Daniel Draguljić,Patrick R. Hof,Jennifer I. Luebke,Christina M. Weaver,Hu He,Xu Yang,Hailin Ma,Zhiheng Xu,Yuzhe Wang,Kwangyeol Baek,Laurel S. Morris,Prantik Kundu,Valerie Voon,Everton J. Agnes,Tim P. Vogels,Martin A. Giese,Pradeep Kuravi,Rufin Vogels,Alexander Seeholzer,William F Podlaski,Rajnish Ranjan,Tim Vogels,Joaquín J. Torres,Fabiano Baroni,Roberto Latorre,Bart Gips,Eric Lowet,Mark Roberts,Peter De Weerd,Ole Jensen,Jan van der Eerden,Abdorreza Goodarzinic,M. D. Niry,Alireza Valizadeh,Aref Pariz,Shervin S. Parsi,Julia M. Warburton,Lucia Marucci,Francesco Tamagnini,John Brown,Krasimira Tsaneva‑Atanasova,Florence I. Kleberg,Jochen Triesch,Bahar Moezzi,Nicolangelo Iannella,Natalie Schaworonkow,Lukas Plogmacher,Mitchell R. Goldsworthy,Brenton Hordacre,Mark D. McDonnell,Michael C. Ridding,Jochen Trisch,Martin Zaptocky,Daniel Šmít,Coralie Fouquet,Alain Trembleau,Sakyasingha Dasgupta,Isao Nishikawa,Kazuyuki Aihara,Taro Toyoizumi,Daniel T. Robb,Nick Mellen,Natalia Toporikova,Rongxiang Tang,Yi-Yuan Tang,Seth A. Kiser,James H. Howard,Julia Goncharenko,Marla Schilstra,Volker Steuber,Sergej O. Voronenko,Benjamin Linder,Tosif Ahamed,Greg J. Stephens,Pierre Yger,Baptiste Lefebvre,Giulia Lia Beatrice Spampinato,Elric Esposito,Marcel Stimberg,Olivier Marre,Hansol Choi,Min-Ho Song,SueYeon Chung,Dan D. Lee,Haim Sompolinsky,Ryan S. Phillips,Jeffrey C. Smith,Alexandra P. Chatzikalymniou,Katie A. Ferguson,N. Alex Cayco Gajic,Claudia Clopath,R. Angus Silver,Padraig Gleeson,Boris Marin,Sadra Sadeh,Adrian Quintana,Matteo Cantarelli,Salvador Dura‑Bernal,William W. Lytton,Andrew P. Davison,Angus Silver,Luozheng Li,Wenhao Zhang,Da-Hui Wang,Sl Wu,Youngjo Song,Sol Park,Ilhwan Choi,Jaeseung Jeong,Hee-Sup Shin,Hannah Choi,Anitha Pasupathy,Eric Shea-Brown,Dongsung Huh,Terrence J. Sejnowski,Simon M. Vogt,Arvind Kumar,Robert Schmidt,Stephen Van Werdt,Steven J. Schiff,Richard Veale,Matthias Scheutz,Sang Wan Lee,Júlia V. Gallinaro,Stefan Rotter,Paula Sanz Leon,Leonid L. Rubchinsky,Chung Ching Cheung,Shivakeshavan Ratnadurai‑Giridharan,Safura Rashid Shomali,Majid Nili Ahmadabadi,Hideaki Shimazaki,Nader Rasuli,Xiaochen Zhao,Malte J. Rasch,Jens Witting,Viola Priesemann,Anna Levina,Joseph T. Lizler,Richard Spinney,Mikail Rubinov,Michael Wibral,Ji Hyun Bak,Jonathan W. Pillow,Yuan Zaho,Memming Park,Jiyoung Kang,Hae-Jeong Park,Jaeson Jang,Se-Bum Paik,Woochul Choi,Changju Lee,Se‑Bum Paik,Min Song,Hyeonsu Lee,Ergin Yilmaz,Velt Baysal,Mahmut Ozer,Daniel Saska,Thomas Nowotny,Ho Ka Chan,Alan Diamond,Christoph S. Hermann,Micha M. Murray,Silvlo Ionta,Axel Hutt,Jérémie Lefebvre,Philipp Weidel,Renato Duarte,Abigail Morrison,Ramakrishnan Iyer,Stefan Mihalas,Mihai A. Petrovici,Luziwei Leng,Oliver Breitwieser,David Stöckel,Ilja Bytschok,Roman Martel,Johannes Bill,Johannes Schemmel,Karlheinz Meier,Timothy B Esler,Anthony N. Burkitt,Robert R. Kerr,Bahman Tahayori,Max Nolte,Michael W. Reimann,Eilif Muler,Henry Markram,Antonio Parziale,Rosa Senatore,Angelo Marcelli,Mounir Maouene,Kaoutar Skiker,Samuel A. Neymotin,Alexandra H. Seidenstein,Peter Lakatos,Terence D. Sanger,Rosemary J. Menzies,Campbell McLauchlan,Sacha J. van Albada,David J. Kedziora,Samuel Neymotin,Cliff C. Kerr,Juhyoung Ryu,Sang-Hun Lee,Joonwon Lee,Hyang Jung Lee,Daeseob Lim,Jung Hoon Lee,Jisung Wang,Heonsoo Lee,Nam Jung,Le Anh Quang,Seung Eu Maeng,Tae Ho Lee,Jae Woo Lee,Chang-hyun Park,Sora Ahn,Jangsup Moon,Yun Seo Choi,Juhee Kim,Sang Beom Jun,Seungjun Lee,Hyang Woon Lee,Sumin Jo,Eunji Jun,Suin Yu,Felix Goetze,Pik‑Yin Lai,Jeehyun Kwag,Guangsheng Liang,Hyun Jae Jang,Marko Filipovi,Ramon Reig,Ad Aertsen,Gilad Silberberg,Claudia Bachmann,Simone Buttler,Heidi I.L. Jacobs,Kim Dillen,Gereon R. Fink,Juraj Kukolja,Daniel Kepple,Hamza Giaffar,Dima Rinberg,Steven Shea,Alex Koulakov,Jyotika Bahuguna,Tom Tetzlaff,Jeanette Hellgren Kotaleski,Tim Kunze,Andre Peterson,Thomas R. Knösche,Minjung Kim,Hojeong Kim,Ji Sung Park,Ji Won Yeon,Sung-Phil Kim,Chungho Lee,Andreas Spiegler,Spase Petkoski,Matias J. Palva,Viktor K. Jirsa,Maria Luisa Saggio,Silvan F. Siep,William C. Stacey,Christophe Bernard,Oh-Hyeon Choung,Yong Jeong,Yong‑il Lee,Jaesung Jeong,Su Hyun Kim,Jeungmin Lee,Jaehyung Kwon,Jerald D. Kralik,Dong-Uk Hwang,Sang-Min Park,Seongkyun Kim,Hyoungkyu Kim,Sewoong Lim,Sangsup Yoon,Choongseok Park,Thomas H Miller,Katie N Clements,Eoon Hye Jr.,Fadi A. Issa,Jeonghun Baek,Shigeyuki Oba,Junichiro Yoshimoto,Kenji Doya,Shin Ishii,Thiago Mosqueiro,Martin F. Strube‑Bloss,Brian H. Smith,Ramon Huerta,Michal Hadrava,Jaroslav Hlinka,Hannah Bos,Moritz Helias,Charles M. Welzig,Zachary J. Harper,Won Sup Kim,In-Seob Shin,Hyeon-Man Baek,Seung Kee Han,René Richter,Julien Vitay,Frederick Beuth,Fred H. Hamker,Bruce P. Graham,Penelope J. Kale,Leonardo L. Gollo,Merav Stern,Larry F. Abbott,Leonid Fedorov,Martin A. Giese,Mohammad Hovaidi Ardestani,V. Srinivasa Chakravarthy,Karishma Chhabria,Ryan T. Philips,Mohammad Java Faraji,Kerstin Preuschoff,Wulfram Gerstner,Jeroen J. Briaire,Randy K. Kalkman,Johan H. M. Frijns,Won Hee Lee,Sophia Frangou,Ben D. Fulcher,Patricia H. P. Tran,Alex Fornito,Stephen V. Gliske,Katherine A. Holman,Christian G. Fink,J. S. Kim,Shang Mu,Kevin L. Briggman,H. Sebastian Seung,Detlef Wegener,Lisa Bohnenkamp,Udo Ernst,Tuomo Mäki‑Marttunen,Anna Devor,Anders M. Dale,Gaute T. Einevoll,Espen Hagen,Glenn T. Lines,Andrew G. Edwards,Aslak Tveito,Johanna Senk,Markus Diesmann,Maximilian Schmidt,Rembrandt Bakker,Kelly Shen,Gleb Bezgin,Claus C. Hilgetag,Haoqi Sun,Olga Sourina,Guang-Bin Huang,Felix Klanner,Cornelia Denk,Katharina Glomb,Adrián Ponce‑Alvarez,Matthieu Gilson,Petra Ritter,Gustavo Deco,Maria A. G. Witek,Eric Clarke,Mads Hansen,Mikkel Wallentin,Morten L. Kringelbach,Peter Vuust,Guido Klingbeil,Erik De Schutter,Weiliang Chen,Sungho Hong,Akira Takashima,Criseida Zamora,Andrew R. Gallimore,Philippa J. Karoly,Dean R. Freestone,Daniel Soundry,Levin Kuhlmann,Liam Paninski,Mark J. Cook,Jaejin Lee,Yonatan I. Fishman,Yale E. Cohen,Luca Cocchi,Yann Sweeney,Soo Hyun Lee,Woo-Sung Jung,Youngsoo Kim,Younginha Jung,Frédéric Chavane,Karthik Soman,Vignesh Muralidharan,Sabyasach Shivkumar,Alekhya Mandall,B. Praga Priyadharsini,Hima Mehta,Braden A. W. Brinkman,Tyler Kekona,Fred Rieke,Eric Shea‑Brown,Michael A. Buice,Maurizio De Pittà,Hugues Berry,Nicolas Brunel,Michael Breakspear,Gary Marsat,Jordan Drew,Phillip D. Chapman,Kevin C. Daly,Samual P. Bradley,Sat Byul Seo,Jianzhong Su,Enge T. Kavalali,Justin Blackwell,LieJune Shiau,Laure Buhry,Kanishka Basnayake,Sue-Hyun Lee,Brandon A. Levy,Chris I. Baker,Timothée Leleu +582 more
TL;DR: Table of contents Functional advantages of cell-type heterogeneity in neural circuits, Dynamics and biomarkers of mental disorders, and Objective criteria for computational neuroscience model selection are presented.
Journal ArticleDOI
The relationship between the claustrum and endopiriform nucleus: a perspective towards consensus on cross-species homology
Jared B. Smith,Kevin D. Alloway,Patrick R. Hof,Rena Orman,David H. Reser,David H. Reser,Akiya Watakabe,Glenn D.R. Watson +7 more
TL;DR: In rodents, it is concluded that the CLA and the dorsal endopiriform nucleus (DEn) are subregions of a larger complex, which likely performs analogous computations and exert similar effects on their respective cortical targets (e.g., sensorimotor versus limbic).