P
Patrick R. Hof
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 834
Citations - 73115
Patrick R. Hof is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Neocortex & Alzheimer's disease. The author has an hindex of 130, co-authored 796 publications receiving 64987 citations. Previous affiliations of Patrick R. Hof include Albert Einstein College of Medicine & National Institutes of Health.
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Selective Frontoinsular von Economo Neuron and Fork Cell Loss in Early Behavioral Variant Frontotemporal Dementia
Eun-Joo Kim,Manu Sidhu,Stephanie E. Gaus,Eric J. Huang,Patrick R. Hof,Bruce L. Miller,Stephen J. DeArmond,William W. Seeley +7 more
TL;DR: This work identifies region-specific neuronal targets in early bvFTD by investigating the selectivity, disease-specificity, laterality, timing, and symptom relevance of frontoinsular VEN and fork cell loss in bv FTD.
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Estrogen Promotes Stress Sensitivity in a Prefrontal Cortex–Amygdala Pathway
TL;DR: Data demonstrate both independent effects of estrogen on pyramidal cell morphology and effects that are interactive with stress, with the BLA-projecting neurons being sensitive to both kinds of effects.
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Neurochemical phenotype of corticocortical connections in the macaque monkey: Quantitative analysis of a subset of neurofilament protein-immunoreactive projection neurons in frontal, parietal, temporal, and cingulate cortices
TL;DR: The hypothesis that neurofilament protein may be crucially linked to the development of selective neuronal vulnerability and subsequent disruption of corticocortical pathways that lead to the severe impairment of cognitive function commonly observed in age‐related dementing disorders is supported.
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Distribution of parvalbumin immunoreactivity in the visual cortex of Old World monkeys and humans.
TL;DR: The macaque visual system has been frequently used as a model for understanding functional aspects of human vision, but there are few studies directly comparing biochemically defined neuronal populations in the visual cortex of the two species.
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Broca's Area Homologue in Chimpanzees (Pan troglodytes): Probabilistic Mapping, Asymmetry, and Comparison to Humans
Natalie M. Schenker,William D. Hopkins,William D. Hopkins,Muhammad A. Spocter,Amy R. Garrison,Cheryl D. Stimpson,Joseph M. Erwin,Patrick R. Hof,Chet C. Sherwood +8 more
TL;DR: It is suggested that Broca's area in the left hemisphere expanded in relative size during human evolution, possibly as an adaptation for the authors' species' language abilities.