P
Patrick R. Hof
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 834
Citations - 73115
Patrick R. Hof is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Neocortex & Alzheimer's disease. The author has an hindex of 130, co-authored 796 publications receiving 64987 citations. Previous affiliations of Patrick R. Hof include Albert Einstein College of Medicine & National Institutes of Health.
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Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy
Gabor G. Kovacs,Isidro Ferrer,Irina Alafuzoff,Johannes Attems,Herbert Budka,Nigel J. Cairns,John F. Crary,Charles Duyckaerts,Bernardino Ghetti,Glenda M. Halliday,James W. Ironside,Seth Love,Ian R. A. Mackenzie,David G. Munoz,Melissa E. Murray,Peter T. Nelson,Hitoshi Takahashi,John Q. Trojanowski,Olaf Ansorge,Thomas Arzberger,Atik Baborie,Thomas G. Beach,Kevin F. Bieniek,Eileen H. Bigio,Istvan Bodi,Brittany N. Dugger,Mel B. Feany,Ellen Gelpi,Stephen M. Gentleman,Giorgio Giaccone,Kimmo J. Hatanpaa,Richard Heale,Patrick R. Hof,Monika Hofer,Tibor Hortobágyi,Kurt A. Jellinger,Gregory A. Jicha,Paul G. Ince,Julia Kofler,Eniko Veronika Kovari,Jillian J. Kril,David M. A. Mann,Radoslav Matej,Ann C. McKee,Catriona McLean,Ivan Milenkovic,Thomas J. Montine,Shigeo Murayama,Edward B. Lee,Jasmin Rahimi,Roberta Diehl Rodriguez,Annemieke J.M. Rozemuller,Julie A. Schneider,Christian Schultz,William W. Seeley,Danielle Seilhean,Colin Smith,Fabrizio Tagliavini,Masaki Takao,Dietmar Rudolf Thal,Jon B. Toledo,Markus Tolnay,Juan C. Troncoso,Harry V. Vinters,Serge Weis,Stephen B. Wharton,Charles L. White,Thomas Wisniewski,John Woulfe,Masahito Yamada,Dennis W. Dicks +70 more
TL;DR: The goal of this proposal is to raise awareness of astroglial tau pathology in the aged brain, facilitating communication among neuropathologists and researchers, and informing interpretation of clinical biomarkers and imaging studies that focus on tau-related indicators.
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Specific pathological Tau protein variants characterize Pick's disease.
André Delacourte,Yves Robitaille,Nicolas Sergeant,Luc Buée,Patrick R. Hof,A. Wattez,Andrée Laroche-Cholette,Jean Mathieu,Pierre Chagnon,Denis Gauvreau +9 more
TL;DR: The 55 and 64 kDa Tau doublet appears to be specific to PiD, less acidic than AD Tau proteins, and well correlated with the presence of PB.
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Comparative cellular analysis of motor cortex in human, marmoset and mouse
Trygve E. Bakken,Nikolas L. Jorstad,Qiwen Hu,Blue B. Lake,Wei Tian,Brian E. Kalmbach,Brian E. Kalmbach,Megan Crow,Rebecca D. Hodge,Fenna M. Krienen,Staci A. Sorensen,Jeroen Eggermont,Zizhen Yao,Brian D. Aevermann,Andrew Aldridge,Anna Bartlett,Darren Bertagnolli,Tamara Casper,Rosa Castanon,Kirsten Crichton,Tanya L. Daigle,Rachel A. Dalley,Nick Dee,Nikolai C. Dembrow,Nikolai C. Dembrow,Dinh Diep,Songlin Ding,Weixiu Dong,Rongxin Fang,Stephan Fischer,Melissa Goldman,Jeff Goldy,Lucas T. Graybuck,Brian R. Herb,Xiaomeng Hou,Jayaram Kancherla,Matthew Kroll,Kanan Lathia,Baldur van Lew,Yang Eric Li,Yang Eric Li,Christine S. Liu,Christine S. Liu,Hanqing Liu,Jacinta Lucero,Anup Mahurkar,Delissa McMillen,Jeremy A. Miller,Marmar Moussa,Joseph R. Nery,Philip R. Nicovich,Sheng-Yong Niu,Sheng-Yong Niu,Joshua Orvis,Julia K. Osteen,Scott F. Owen,C. Palmer,C. Palmer,Thanh Pham,Nongluk Plongthongkum,Olivier Poirion,Nora Reed,Christine Rimorin,Angeline Rivkin,William J. Romanow,Adriana E. Sedeno-Cortes,Kimberly Siletti,Saroja Somasundaram,Josef Sulc,Michael Tieu,Amy Torkelson,Herman Tung,Xinxin Wang,Fangming Xie,Anna Marie Yanny,Renee Zhang,Seth A. Ament,M. Margarita Behrens,Héctor Corrada Bravo,Jerold Chun,Alexander Dobin,Jesse Gillis,Ronna Hertzano,Patrick R. Hof,Thomas Höllt,Gregory D. Horwitz,C. Dirk Keene,Peter V. Kharchenko,Andrew L. Ko,Andrew L. Ko,Boudewijn P. F. Lelieveldt,Boudewijn P. F. Lelieveldt,Chongyuan Luo,Eran A. Mukamel,Antonio Pinto-Duarte,Sebastian Preissl,Aviv Regev,Bing Ren,Bing Ren,Richard H. Scheuermann,Richard H. Scheuermann,Richard H. Scheuermann,Kimberly A. Smith,William J. Spain,William J. Spain,Owen White,Christof Koch,Michael Hawrylycz,Bosiljka Tasic,Evan Z. Macosko,Steven A. McCarroll,Steven A. McCarroll,Jonathan T. Ting,Jonathan T. Ting,Hongkui Zeng,Kun Zhang,Guoping Feng,Guoping Feng,Guoping Feng,Joseph R. Ecker,Sten Linnarsson,Ed S. Lein +121 more
TL;DR: The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally conserved across mammals using high-throughput transcriptomic and epigenomic profiling of more than 450k single nuclei in humans, marmoset monkeys and mice as mentioned in this paper.
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Selective disconnection of specific visual association pathways in cases of Alzheimer's disease presenting with Balint's syndrome.
TL;DR: In some cases of AD, the particular psychological and neurological symptomatology may be caused by the selective loss of specific corticocortical systems, as reflected in the differential distribution of the neuropathological markers of the disease.
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Spindle neurons of the human anterior cingulate cortex.
TL;DR: Observations indicate that the spindle cells of the human cingulate cortex represent a morphological subpopulation of pyramidal neurons whose restricted distribution may be associated with functionally distinct areas.