P
Patrick R. Hof
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 834
Citations - 73115
Patrick R. Hof is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Neocortex & Alzheimer's disease. The author has an hindex of 130, co-authored 796 publications receiving 64987 citations. Previous affiliations of Patrick R. Hof include Albert Einstein College of Medicine & National Institutes of Health.
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Journal ArticleDOI
Stereology of the Neocortex in Odontocetes: Qualitative, Quantitative, and Functional Implications
TL;DR: The generally higher density of cortical layer III in Tursiops suggests a higher connectivity of this layer in view of the more agile and complicated behavior of these gregarious animals including versatile phonation by complex sound and ultrasound signals.
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Gene-Environment Interaction Research and Transgenic Mouse Models of Alzheimer's Disease (Erratum)
Leonidas Chouliaras,Annerieke S.R. Sierksma,G. Kenis,Jos Prickaerts,Marijke A. M. Lemmens,I. Brasnjevic,E. L. van Donkelaar,Pilar Martinez-Martinez,Mario Losen,M. De Baets,N. Kholod,F. W. van Leeuwen,Patrick R. Hof,J. van Os,H.W.M. Steinbusch,D.L.A. van den Hove,B Rutten +16 more
TL;DR: This work aims to provide a clear picture of the aims and objectives of this research and its aims are likely to have changed over time from that of a prior study.
Journal ArticleDOI
Gray matter volume of the anterior insular cortex and social networking
Alfredo Spagna,Alexander J. Dufford,Qiong Wu,Tingting Wu,Weihao Zheng,Edgar E. Coons,Patrick R. Hof,Bin Hu,Bin Hu,Yanhong Wu,Jin Fan +10 more
TL;DR: The converging results from the two groups suggest that the AIC supports network‐level social interactions, a structure involved in basic and high‐level cognition, and social networking.
Journal Article
Cerebrospinal fluid markers in differential diagnosis of Alzheimer's disease and vascular dementia.
Marina Boban,Kristina Grbić,Mihovil Mladinov,Patrick R. Hof,Christine Süssmair,Nibal Ackl,Gabrijela Stanić,Benedikt Bader,Adrian Danek,Goran Šimić +9 more
TL;DR: Preliminary data on a small group of selected subjects suggest that the CSF t-t Tau and p-tau199 levels are useful markers for differentiating AD from VaD.
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Increased expression of RXRα in dementia: an early harbinger for the cholesterol dyshomeostasis?
Afia Akram,James Schmeidler,Pavel Katsel,Patrick R. Hof,Vahram Haroutunian,Vahram Haroutunian +5 more
TL;DR: Findings suggest that LXR/RXR-induced upregulation of ABCA1 and ApoE levels may be the molecular determinants of cholesterol dyshomeostasis and of the accompanying dementia observed in AD.