R
Richard Durbin
Researcher at University of Cambridge
Publications - 337
Citations - 247542
Richard Durbin is an academic researcher from University of Cambridge. The author has contributed to research in topics: Genome & Population. The author has an hindex of 125, co-authored 319 publications receiving 207192 citations. Previous affiliations of Richard Durbin include Wellcome Trust Sanger Institute & University of Manchester.
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Journal ArticleDOI
A conserved sequence motif in 3' untranslated regions of ribosomal protein mRNAs in nematodes.
Ashwin Hajarnavis,Richard Durbin +1 more
TL;DR: Analysis of the region around the polyadenylation signal in many ribosomal protein mRNAs indicates the conservation of a sequence motif UUGUU occurring both before and immediately after the polyADS signal, suggesting that this signal may be involved in translation or other message-level regulation of ribosome genes in C. elegans.
Posted ContentDOI
Removing reference bias in ancient DNA data analysis by mapping to a sequence variation graph
Rui Martiniano,Erik Garrison,Erik Garrison,Eppie R. Jones,Andrea Manica,Richard Durbin,Richard Durbin +6 more
TL;DR: In this article, the authors used vg to align multiple previously published aDNA samples to a variation graph containing 1000 Genome Project variants, and compared these with the same data aligned with bwa to the human linear reference genome.
Journal ArticleDOI
Did our species evolve in subdivided populations across Africa, and Why does it matter?
Eleanor M. L. Scerri,Mark G. Thomas,Andrea Manica,Philipp Gunz,Jay T. Stock,Chris Stringer,Matt Grove,Huw S. Groucutt,Axel Timmermann,G. Philip Rightmire,Christian A. Tryon,Nick Drake,Alison S. Brooks,Robin Dennell,Richard Durbin,Brenna M. Henn,Julia A. Lee-Thorp,Peter B deMenocal,Michael D. Petraglia,Jessica C. Thompson,Aylwyn Scally,Lounès Chikhi +21 more
Posted ContentDOI
Fast and scalable genome-wide inference of local tree topologies from large number of haplotypes based on tree consistent PBWT data structure
TL;DR: This work describes a new approach for fast and scalable generation of local tree topologies relating large numbers of haplotypes based on a data structure which it calls tree consistent, a modification of data structure introduced by R. Durbin (2014).
Posted ContentDOI
Contrasting genome dynamics between domesticated and wild yeasts
Jia-Xing Yue,Jing Li,Louise Aigrain,Johan Hallin,Karl Persson,Karen Oliver,Anders Bergström,Paul Coupland,Jonas Warringer,Marco Cosentino Lagomarsino,Gilles Fischer,Richard Durbin,Gianni Liti +12 more
TL;DR: High-resolution view of structural dynamics uncovers that, in chromosomal cores, S. paradoxus exhibits higher accumulation rate of balanced structural rearrangements (inversions, translocations and transpositions) whereas S. cerevisiae accumulates unbalanced rearrangement more rapidly.