R
Richard Durbin
Researcher at University of Cambridge
Publications - 337
Citations - 247542
Richard Durbin is an academic researcher from University of Cambridge. The author has contributed to research in topics: Genome & Population. The author has an hindex of 125, co-authored 319 publications receiving 207192 citations. Previous affiliations of Richard Durbin include Wellcome Trust Sanger Institute & University of Manchester.
Papers
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Posted ContentDOI
The rate of false polymorphisms introduced when imputing genotypes from global imputation panels
Ida Surakka,Antti-Pekka Sarin,Sanni Ruotsalainen,Richard Durbin,Salomaa,Mark J. Daly,Aarno Palotie,Samuli Ripatti +7 more
TL;DR: The rate of false positive variants introduced by the imputation of Finnish genotype data using global reference panels using Haplotype Reference Consortium1; HRC, and the 1000Genomes project Phase I3; 1000G is evaluated and the results are compared to a Finnish population-specific reference panel combining whole genome and exome sequenced samples.
Posted ContentDOI
souporcell: Robust clustering of single cell RNAseq by genotype and ambient RNA inference without reference genotypes
Haynes Heaton,Arthur M. Talman,Andrew J Knights,Maria Imaz,Maria Imaz,Daniel J. Gaffney,Richard Durbin,Martin Hemberg,Mara K. N. Lawniczak +8 more
TL;DR: Souporcell is a novel method to cluster cells using only the genetic variants detected within the scRNAseq reads that achieves high accuracy on genotype clustering, doublet detection, and ambient RNA estimation as demonstrated across a wide range of challenging scenarios.
Journal Article
The DNA sequence and biological annotation of human chromosome 1 (vol 441, pg 315, 2006)
Simon G. Gregory,K F Barlow,Kirsten McLay,Rajinder Kaul,David Swarbreck,Andrew Dunham,Carol Scott,Kerstin Howe,Kathryn Woodfine,Cca Spencer,Matthew Jones,Christopher J. Gillson,S. Searle,Yi Zhou,Felix Kokocinski,L McDonald,R Evans,Katharine A. Phillips,A Atkinson,R Cooper,C Jones,Rebekah Hall,T D Andrews,Christine Lloyd,R Ainscough,J P Almeida,K D Ambrose,F Anderson,R. W. Andrew,Ris Ashwell,K Aubin,A K Babbage,C L Bagguley,J Bailey,Ruby Banerjee,Helen Beasley,Graeme Bethel,Christine P. Bird,S Bray-Allen,J Y Brown,A J Brown,S P Bryant,D Buckley,D C Burford,Wdh Burrill,John Burton,Jacqueline M. Bye,C Carder,J C Chapman,S Y Clark,G Clarke,C M Clee,S. M. Clegg,Cobley,R. E. Collier,N Corby,G. J. Coville,Joy Davies,Rebecca Deadman,Pawandeep Dhami,Oliver M. Dovey,Matthew Dunn,M Earthrowl,A. G. Ellington,H Errington,L M Faulkner,Adam Frankish,J Frankland,Lisa French,P Garner,J Garnett,Mrj Ghori,Richard Gibson,L M Gilby,Will Gillett,Rebecca Glithero,Darren Grafham,Susan M. Gribble,C Griffiths,Sam Griffiths-Jones,Russell J. Grocock,S Hammond,Esi Harrison,E. Hart,Eric Haugen,Paul Heath,S. Holmes,Kathryn E. Holt,Philip Howden,Adrienne Hunt,Sarah E. Hunt,G Hunter,J Isherwood,R. James,Chris Johnson,D. Johnson,A Joy,M. Kay,J K Kershaw,M. Kibukawa,A M Kimberley,A. King,Andrew J Knights,Heena V. Lad,Gavin K. Laird,Cordelia Langford,S Lawlor,Daniel Leongamornlert,D. M. Lloyd,Jane E. Loveland,J Lovell,Michael J. Lush,Rachel Lyne,Sancha Martin,M Mashreghi-Mohammadi,Lucy Matthews,Nsw Matthews,Stuart McLaren,Sarah Milne,S. Mistry,Mjf Moore,T Nickerson,C. Odell,Karen Oliver,A. Palmeiri,Sophie Palmer,Richard Pandian,Anne Parker,D. Patel,A. V. Pearce,A I Peck,Sarah Pelan,Karen A. Phelps,Benjamin Phillimore,Robert W. Plumb,K M Porter,E Prigmore,Jeena Rajan,Charles F. Raymond,Greg W. Rouse,Channakhone Saenphimmachak,Harminder Sehra,E Sheridan,Ratna Shownkeen,Sarah Sims,C. D. Skuce,Michelle Smith,Charles A. Steward,Sankaran Subramanian,N Sycamore,Alan Tracey,A Tromans,Z. Van Helmond,Mwjm Wallis,Simon D. M. White,S. Whitehead,Jane E. Wilkinson,David Willey,H. Williams,Laurens G. Wilming,Paul Wray,Z. Wu,Alan Coulson,M. Vaudin,John Sulston,Richard Durbin,Tim Hubbard,Richard Wooster,Ian Dunham,Nigel P. Carter,G. McVean,Mark T. Ross,Jen Harrow,Maynard V. Olson,Stephan Beck,Jane Rogers,Bentley +176 more
Journal ArticleDOI
A haplotype-resolved, de novo genome assembly for the wood tiger moth (Arctia plantaginis) through trio binning
Eugenie C Yen,Shane A. McCarthy,Shane A. McCarthy,Juan A. Galarza,Tomas N Generalovic,Sarah Pelan,Petr Nguyen,Petr Nguyen,Joana I. Meier,Ian A. Warren,Johanna Mappes,Richard Durbin,Richard Durbin,Chris D. Jiggins +13 more
TL;DR: This assembly is one of the highest quality genomes available for Lepidoptera, supporting trio binning as a potent strategy for assembling heterozygous genomes, and provides genomic insights into the geographic population structure of A. plantaginis.
Posted ContentDOI
A high-quality, chromosome-level genome assembly of the Black Soldier Fly (Hermetia Illucens L.)
Tomas N Generalovic,Shane A. McCarthy,Shane A. McCarthy,Ian A. Warren,Jonathan Wood,James Torrance,Ying Sims,Michael A. Quail,Kerstin Howe,Miha Pipan,Richard Durbin,Richard Durbin,Chris D. Jiggins +12 more
TL;DR: A high-quality chromosome-scale genome assembly of the Black Soldier Fly revealing six autosomes and the identification of an X chromosome is generated and this reference sequence will provide an essential tool for future genetic modifications, functional and population genomics.