R
Richard Durbin
Researcher at University of Cambridge
Publications - 337
Citations - 247542
Richard Durbin is an academic researcher from University of Cambridge. The author has contributed to research in topics: Genome & Population. The author has an hindex of 125, co-authored 319 publications receiving 207192 citations. Previous affiliations of Richard Durbin include Wellcome Trust Sanger Institute & University of Manchester.
Papers
More filters
Journal ArticleDOI
A large genome center's improvements to the Illumina sequencing system.
Michael A. Quail,Iwanka Kozarewa,Frances Smith,Aylwyn Scally,Philip J. Stephens,Richard Durbin,Harold Swerdlow,Daniel J. Turner +7 more
TL;DR: A set of improvements are described to the standard Illumina protocols to make the library preparation more reliable in a high-throughput environment, to reduce bias, tighten insert size distribution and reliably obtain high yields of data.
Journal ArticleDOI
Identifying and removing haplotypic duplication in primary genome assemblies.
Dengfeng Guan,Dengfeng Guan,Shane A. McCarthy,Jonathan Wood,Kerstin Howe,Yadong Wang,Richard Durbin,Richard Durbin +7 more
TL;DR: A novel tool, purge_dups, is presented, that uses sequence similarity and read depth to automatically identify and remove both haplotigs and heterozygous overlaps and can reduce heter allele duplication and increase assembly continuity while maintaining completeness of the primary assembly.
Journal ArticleDOI
The InterPro Database, 2003 brings increased coverage and new features
Nicola Mulder,Rolf Apweiler,Teresa K. Attwood,Amos Marc Bairoch,Daniel Barrell,Alex Bateman,David Binns,Margaret Biswas,Paul Bradley,Peer Bork,Phillip Bucher,Richard R. Copley,Emmanuel Courcelle,Ujjwal Das,Richard Durbin,Laurent Falquet,Wolfgang Fleischmann,Sam Griffiths-Jones,Daniel H. Haft,Nicola Harte,Nicolas Hulo,Daniel Kahn,Alexander Kanapin,Maria Krestyaninova,Rodrigo Lopez,Ivica Letunic,David M. Lonsdale,Ville Silventoinen,Sandra Orchard,Marco Pagni,David Peyruc,Chris P. Ponting,Jeremy D. Selengut,Florence Servant,Christian J. A. Sigrist,Robert M. Vaughan,Evgeny M. Zdobnov +36 more
TL;DR: The latest release of InterPro contains 5629 entries describing 4280 families, 1239 domains, 95 repeats and 15 post-translational modifications, an increase of nearly 15% since the inception of Inter pro.
Journal ArticleDOI
Insights into hominid evolution from the gorilla genome sequence
Aylwyn Scally,Julien Y. Dutheil,LaDeana W. Hillier,Gregory E. Jordan,Ian Goodhead,Javier Herrero,Asger Hobolth,Tuuli Lappalainen,Thomas Mailund,Tomas Marques-Bonet,Tomas Marques-Bonet,Tomas Marques-Bonet,Shane A. McCarthy,Stephen H. Montgomery,Petra C. Schwalie,Y. Amy Tang,Michelle C Ward,Yali Xue,Bryndis Yngvadottir,Can Alkan,Lars Nørvang Andersen,Qasim Ayub,Edward V. Ball,Kathryn Beal,Brenda J. Bradley,Brenda J. Bradley,Yuan Chen,Chris Clee,Stephen Fitzgerald,Tina Graves,Yong Gu,Paul Heath,Andreas Heger,Emre Karakoc,Anja Kolb-Kokocinski,Gavin K. Laird,Gerton Lunter,Stephen Meader,Matthew Mort,James C. Mullikin,Kasper Munch,Timothy D. O’Connor,Andrew David Phillips,Javier Prado-Martinez,Anthony Rogers,Saba Sajjadian,Dominic Schmidt,Katy Shaw,Jared T. Simpson,Peter D. Stenson,Daniel J. Turner,Linda Vigilant,Albert J. Vilella,Weldon Whitener,Baoli Zhu,David Neil Cooper,Pieter J. de Jong,Emmanouil T. Dermitzakis,Evan E. Eichler,Paul Flicek,Nick Goldman,Nicholas I. Mundy,Zemin Ning,Duncan T. Odom,Duncan T. Odom,Chris P. Ponting,Michael A. Quail,Oliver A. Ryder,Stephen M. J. Searle,Wesley C. Warren,Richard K. Wilson,Mikkel H. Schierup,Jane Rogers,Chris Tyler-Smith,Richard Durbin +74 more
TL;DR: A comparison of protein coding genes reveals approximately 500 genes showing accelerated evolution on each of the gorilla, human and chimpanzee lineages, and evidence for parallel acceleration, particularly of genes involved in hearing.
Journal ArticleDOI
Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species
Keith Bradnam,Joseph Fass,Anton Alexandrov,Paul Baranay,Michael Bechner,Inanc Birol,Sébastien Boisvert,Jarrod Chapman,Guillaume Chapuis,Guillaume Chapuis,Rayan Chikhi,Rayan Chikhi,Hamidreza Chitsaz,Wen-Chi Chou,Jacques Corbeil,Cristian Del Fabbro,T. Roderick Docking,Richard Durbin,Dent Earl,Scott J. Emrich,Pavel Fedotov,Nuno A. Fonseca,Ganeshkumar Ganapathy,Richard A. Gibbs,Sante Gnerre,Elenie Godzaridis,Steve Goldstein,Matthias Haimel,Giles Hall,David Haussler,Joseph B. Hiatt,Isaac Ho,Jason T. Howard,Martin Hunt,Shaun D. Jackman,David B. Jaffe,Erich D. Jarvis,Huaiyang Jiang,Sergey Kazakov,Paul J. Kersey,Jacob O. Kitzman,James R. Knight,Sergey Koren,Tak-Wah Lam,Dominique Lavenier,Dominique Lavenier,François Laviolette,Yingrui Li,Zhenyu Li,Binghang Liu,Yue Liu,Ruibang Luo,Iain MacCallum,Matthew D. MacManes,Nicolas Maillet,Sergey Melnikov,Bruno Vieira,Delphine Naquin,Zemin Ning,Thomas D. Otto,Benedict Paten,Octávio S. Paulo,Adam M. Phillippy,Francisco Pina-Martins,Michael Place,Dariusz Przybylski,Xiang Qin,Carson Qu,Filipe J. Ribeiro,Stephen Richards,Daniel S. Rokhsar,Daniel S. Rokhsar,J. Graham Ruby,J. Graham Ruby,Simone Scalabrin,Michael C. Schatz,David C. Schwartz,Alexey Sergushichev,Ted Sharpe,Timothy I. Shaw,Jay Shendure,Yujian Shi,Jared T. Simpson,Henry Song,Fedor Tsarev,Francesco Vezzi,Riccardo Vicedomini,Jun Wang,Kim C. Worley,Shuangye Yin,Siu-Ming Yiu,Jianying Yuan,Guojie Zhang,Hao Zhang,Shiguo Zhou,Ian F Korf +95 more
TL;DR: The Assemblathon 2 as mentioned in this paper presented a variety of sequence data to be assembled for three vertebrate species (a bird, a fish, and a snake) from 21 participating teams.