Richard Durbin

TL;DR: The goals of this conference were to reach a world class standard of science with a large number of contributions from within Africa, to initiate an exchange between African and international researchers and to identify challenges and opportunities for evolutionary genomics research in Africa.

TL;DR: The bulk of space taken up by NGS sequencing CRAM files consists of per-base quality values, offering an opportunity for space saving, and a 17 fold reduction in quality storage can be achieved while maintaining variant calling accuracy.

TL;DR: This work searches a database for a local alignment to a query under a typical scoring scheme such as PAM120 or BLOSUM62 and finds a set of tables that permit one to eliminate a large fraction of the dynamic programming matrix from consideration and compute several steps of the remainder with a single table lookup.

TL;DR: NNoVAE is presented, a method using Nearest Neighbours (NN) and Variational Autoencoders (VAE), which is applied to k-mers resulting from the ANOSPP amplicon sequences in order to hierarchically assign species identity, and is used to survey Anopheles species diversity and Plasmodium transmission patterns through space and time on a large scale.

TL;DR: In this article, the authors carried out low-read depth (4-10x) whole-genome sequencing in 568 individuals from three Italian founder populations, and compared it to data from other Italian and European populations from the 1000 Genomes Project.