R
Richard Durbin
Researcher at University of Cambridge
Publications - 337
Citations - 247542
Richard Durbin is an academic researcher from University of Cambridge. The author has contributed to research in topics: Genome & Population. The author has an hindex of 125, co-authored 319 publications receiving 207192 citations. Previous affiliations of Richard Durbin include Wellcome Trust Sanger Institute & University of Manchester.
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Journal ArticleDOI
Pfam 3.1: 1313 multiple alignments and profile HMMs match the majority of proteins
TL;DR: Pfam is a collection of multiple alignments and profile hidden Markov models of protein domain families that contains 1313 families and over 54% of proteins in SWISS-PROT-35 and SP-TrEMBL-5 match a Pfam family.
Posted ContentDOI
Towards complete and error-free genome assemblies of all vertebrate species
Arang Rhie,Shane A. McCarthy,Olivier Fedrigo,Joana Damas,Giulio Formenti,Sergey Koren,Marcela Uliano-Silva,William Chow,Arkarachai Fungtammasan,Gregory Gedman,Lindsey J. Cantin,Françoise Thibaud-Nissen,Leanne Haggerty,Chul Hee Lee,Byung June Ko,J. H. Kim,Iliana Bista,Michelle Smith,Bettina Haase,Jacquelyn Mountcastle,Sylke Winkler,Sadye Paez,Jason T. Howard,Sonja C. Vernes,Tanya M. Lama,Frank Grützner,Wesley C. Warren,Christopher N. Balakrishnan,Dave W Burt,Jimin George,Matthew T. Biegler,David Iorns,Andrew Digby,Daryl Eason,Taylor Edwards,Mark Wilkinson,George F. Turner,Axel Meyer,Andreas F. Kautt,Paolo Franchini,H. William Detrich,Hannes Svardal,Maximilian Wagner,Gavin J. P. Naylor,Martin Pippel,Milan Malinsky,Mark Mooney,Maria Simbirsky,Brett T. Hannigan,Trevor Pesout,Marlys L. Houck,Ann C Misuraca,Sarah B. Kingan,Richard Hall,Zev N. Kronenberg,Jonas Korlach,Ivan Sović,Christopher Dunn,Zemin Ning,Alex Hastie,Joyce V. Lee,Siddarth Selvaraj,Richard E. Green,Nicholas H. Putnam,Jay Ghurye,Erik Garrison,Ying Sims,Joanna Collins,Sarah Pelan,James Torrance,Alan Tracey,Jonathan Wood,Dengfeng Guan,Sarah E. London,David F. Clayton,Claudio V. Mello,Samantha R. Friedrich,Peter V. Lovell,Ekaterina Osipova,Farooq O. Al-Ajli,Simona Secomandi,Heebal Kim,Constantina Theofanopoulou,Yang Zhou,Robert S. Harris,Kateryna D. Makova,Paul Medvedev,Jinna Hoffman,Patrick Masterson,Karen Clark,Fergal J. Martin,Kevin L. Howe,Paul Flicek,Brian P. Walenz,Woori Kwak,Hiram Clawson,Mark Diekhans,Luis R Nassar,Benedict Paten,Robert H. S. Kraus,Harris A. Lewin,Andrew J. Crawford,M. Thomas P. Gilbert,Guojie Zhang,Byrappa Venkatesh,Robert W. Murphy,Klaus-Peter Koepfli,Beth Shapiro,Warren E. Johnson,Federica Di Palma,Tomas Marques-Bonet,Emma C. Teeling,Tandy Warnow,Jennifer A. Marshall Graves,Oliver A. Ryder,David Haussler,Stephen J. O'Brien,Kerstin Howe,Eugene W. Myers,Richard Durbin,Adam M. Phillippy,Erich D. Jarvis +121 more
TL;DR: The Vertebrate Genomes Project is embarked on, an effort to generate high-quality, complete reference genomes for all ~70,000 extant vertebrate species and help enable a new era of discovery across the life sciences.
Journal ArticleDOI
Earth BioGenome Project: Sequencing life for the future of life.
Harris A. Lewin,Gene E. Robinson,W. John Kress,William J. Baker,Jonathan A. Coddington,Keith A. Crandall,Richard Durbin,Richard Durbin,Scott V. Edwards,Félix Forest,M. Thomas P. Gilbert,M. Thomas P. Gilbert,Melissa M. Goldstein,Igor V. Grigoriev,Igor V. Grigoriev,Kevin J. Hackett,David Haussler,Erich D. Jarvis,Warren E. Johnson,Aristides Patrinos,Stephen Richards,Juan Carlos Castilla-Rubio,Marie-Anne Van Sluys,Pamela S. Soltis,Xun Xu,Huanming Yang,Guojie Zhang,Guojie Zhang +27 more
TL;DR: A perspective on the Earth BioGenome Project (EBP), a moonshot for biology that aims to sequence, catalog, and characterize the genomes of all of Earth’s eukaryotic biodiversity over a period of 10 years, is presented.
Journal ArticleDOI
Assemblathon 1: A competitive assessment of de novo short read assembly methods
Dent Earl,Keith Bradnam,John St. John,Aaron E. Darling,Dawei Lin,Joseph Fass,Hung On Ken Yu,Vince Buffalo,Daniel R. Zerbino,Mark Diekhans,Ngan Nguyen,Pramila N. Ariyaratne,Wing-Kin Sung,Wing-Kin Sung,Zemin Ning,Matthias Haimel,Jared T. Simpson,Nuno A. Fonseca,Inanc Birol,T. Roderick Docking,Isaac Ho,Daniel S. Rokhsar,Rayan Chikhi,Dominique Lavenier,Dominique Lavenier,Guillaume Chapuis,Delphine Naquin,Delphine Naquin,Nicolas Maillet,Nicolas Maillet,Michael C. Schatz,David R. Kelley,Adam M. Phillippy,Sergey Koren,Shiaw-Pyng Yang,Wei Wu,Wen-Chi Chou,Anuj Srivastava,Timothy I. Shaw,J. Graham Ruby,J. Graham Ruby,Peter Skewes-Cox,Peter Skewes-Cox,Miguel Betegon,Miguel Betegon,Michelle Dimon,Michelle Dimon,Victor V. Solovyev,Igor Seledtsov,Petr Kosarev,Denis Vorobyev,Ricardo H. Ramirez-Gonzalez,Richard M. Leggett,Dan MacLean,Fangfang Xia,Ruibang Luo,Zhenyu Li,Yinlong Xie,Binghang Liu,Sante Gnerre,Iain MacCallum,Dariusz Przybylski,Filipe J. Ribeiro,Shuangye Yin,Ted Sharpe,Giles Hall,Paul J. Kersey,Richard Durbin,Shaun D. Jackman,Jarrod Chapman,Xiaoqiu Huang,Joseph L. DeRisi,Mario Caccamo,Yingrui Li,David B. Jaffe,Richard E. Green,David Haussler,Ian F Korf,Benedict Paten +78 more
TL;DR: The Assemblathon 1 competition is described, which aimed to comprehensively assess the state of the art in de novo assembly methods when applied to current sequencing technologies, and it is established that it is possible to assemble the genome to a high level of coverage and accuracy.
Journal ArticleDOI
Revising the human mutation rate: implications for understanding human evolution
Aylwyn Scally,Richard Durbin +1 more
TL;DR: The implications of a lower-than-expected mutation rate in relation to the timescale of human evolution are discussed.