Richard Durbin

TL;DR: The extent, causes, and effects of naturally occurring variation in expression and sequence of small RNAs from adipose tissue in relation to genotype, gene expression, and metabolic traits in the MuTHER reference cohort are characterised and a quantitative picture of small RNA expression variation in the human population is given.

TL;DR: This study applies the Bayesian network based model in a new phasing algorithm, called systematic long‐range phasing (SLRP), that can capitalize on the close genetic relationships in isolated founder populations, and shows with simulated and real genome‐wide genotype data that SLRP substantially reduces the rate of phasing errors compared to previous phasing algorithms.

TL;DR: In this paper, a high-content platform for phenotypic analysis of human induced pluripotent stem cells (iPSC) lines is described, where cells are dissociated and seeded as single cells onto 96-well plates coated with fibronectin at three different concentrations.

TL;DR: A large-scale metagenomic analysis of plant and mammal environmental DNA reveals complex ecological changes across the circumpolar region over the past 50,000 years, as biota responded to changing climates, culminating in the postglacial extinction of large mammals and emergence of modern ecosystems as discussed by the authors.

TL;DR: Analyses of high-coverage genome sequences from 54 diverse human populations reveal an excess of previously undocumented private genetic variation in southern and central Africa and in Oceania and the Americas, but an absence of fixed, private variants between major geographical regions.