Rudolf Uher

TL;DR: In this article, the authors examined whether stressful life events experienced prior to and during treatment interact with neuroticism to predict response to 16-week pharmacotherapy for major depressive disorder (MDD).

TL;DR: The second-line treatment recommendation for STPP captures the emerging nature of the evidence and clinical utility of STPP and the issues of multiple divergent findings in that article and the use of many small and methodologically challenged studies do not allow for a clear, unequivocal conclusion.

TL;DR: In this article , the authors investigated the impact of BDNF polymorphism on antidepressant treatment outcomes and hippocampal volume changes during antidepressant treatment and found that BDNF expression can be altered due to genetic polymorphism in rs6265 (Valene [Val] replaced by Methionine [Met] allele).

TL;DR: In this article , the authors show that if heterogeneities in cohort-specific h S N P 2 exist, or if genetic correlations between cohorts are less than one, the out-of-sample prediction R2 will be greater than h S n P 2 and show the validity of their derivations with real data from a binary trait (major depression) and a continuous trait (educational attainment).