R
Rudolf Uher
Researcher at Dalhousie University
Publications - 350
Citations - 28239
Rudolf Uher is an academic researcher from Dalhousie University. The author has contributed to research in topics: Major depressive disorder & Bipolar disorder. The author has an hindex of 77, co-authored 314 publications receiving 23342 citations. Previous affiliations of Rudolf Uher include Karolinska Institutet & Duke University.
Papers
More filters
Journal ArticleDOI
Symptom Dimension of Interest-Activity Indicates Need for Aripiprazole Augmentation of Escitalopram in Major Depressive Disorder: A CAN-BIND-1 Report
Rudolf Uher,Rudolf Uher,Benicio N. Frey,Benicio N. Frey,Lena C. Quilty,Lena C. Quilty,Susan Rotzinger,Pierre Blier,Jane A. Foster,Daniel J. Müller,Daniel J. Müller,Arun V. Ravindran,Arun V. Ravindran,Claudio N. Soares,Gustavo Turecki,Sagar V. Parikh,Roumen Milev,Glenda MacQueen,Raymond W. Lam,Sidney H. Kennedy,Can-Bind Investigator Team +20 more
TL;DR: Individuals with prominent loss of interest and reduction in activity benefit less from escitalopram monotherapy and more from aripiprazole augmentation, guided by interest-activity symptoms.
Posted ContentDOI
Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders
Gabriëlla A.M. Blokland,Jakob Grove,Chia-Yen Chen,Chia-Yen Chen,Chris Cotsapas,Chris Cotsapas,Stuart A. Tobet,Stuart A. Tobet,Robert Handa,Robert Handa,David St Clair,Todd Lencz,Todd Lencz,Bryan J. Mowry,Bryan J. Mowry,Sathish Periyasamy,Sathish Periyasamy,Murray J. Cairns,Paul A. Tooney,Jing Qin Wu,Brian Kelly,George Kirov,Patrick F. Sullivan,Patrick F. Sullivan,Aiden Corvin,Brien P. Riley,Tõnu Esko,Lili Milani,Erik G. Jönsson,Erik G. Jönsson,Aarno Palotie,Aarno Palotie,Aarno Palotie,Hannelore Ehrenreich,Martin Begemann,Agnes A. Steixner-Kumar,Pak C. Sham,Pak C. Sham,Nakao Iwata,Daniel R. Weinberger,Pablo V. Gejman,Pablo V. Gejman,Alan R. Sanders,Alan R. Sanders,Joseph D. Buxbaum,Dan Rujescu,Dan Rujescu,Ina Giegling,Ina Giegling,Bettina Konte,Annette M. Hartmann,Elvira Bramon,Robin M. Murray,Michele T. Pato,Michele T. Pato,Jimmy Lee,Ingrid Melle,Espen Molden,Roel A. Ophoff,Roel A. Ophoff,Roel A. Ophoff,Andrew McQuillin,Nicholas Bass,Rolf Adolfsson,Anil K. Malhotra,Anil K. Malhotra,Nicholas G. Martin,Nicholas G. Martin,Janice M. Fullerton,Janice M. Fullerton,Philip B. Mitchell,Peter R. Schofield,Peter R. Schofield,Andreas J. Forstner,Andreas J. Forstner,Franziska Degenhardt,Franziska Degenhardt,Sabrina K. Schaupp,Ashley L. Comes,Manolis Kogevinas,Jose Guzman-Parra,Andreas Reif,Fabian Streit,Lea Sirignano,Sven Cichon,Maria Grigoroiu-Serbanescu,Joanna Hauser,Jolanta Lissowska,Fermín Mayoral,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Beata Świątkowska,Thomas G. Schulze,Markus M. Nöthen,Marcella Rietschel,John R. Kelsoe,Marion Leboyer,Marion Leboyer,Stéphane Jamain,Stéphane Jamain,Bruno Etain,Frank Bellivier,John B. Vincent,Martin Alda,Martin Alda,Claire O'Donovan,Pablo Cervantes,Joanna M. Biernacka,Mark A. Frye,Susan L. McElroy,Laura J. Scott,Eli A. Stahl,Eli A. Stahl,Mikael Landén,Mikael Landén,Marian L. Hamshere,Olav B. Smeland,Srdjan Djurovic,Srdjan Djurovic,Arne E. Vaaler,Ole A. Andreassen,Bernhard T. Baune,Bernhard T. Baune,Tracy Air,Martin Preisig,Rudolf Uher,Douglas F. Levinson,Myrna M. Weissman,James B. Potash,Jianxin Shi,James A. Knowles,Roy H. Perlis,Roy H. Perlis,Susanne Lucae,Dorret I. Boomsma,Dorret I. Boomsma,Brenda W.J.H. Penninx,Jouke-Jan Hottenga,Jouke-Jan Hottenga,Eco J. C. de Geus,Eco J. C. de Geus,Gonneke Willemsen,Gonneke Willemsen,Yuri Milaneschi,Henning Tiemeier,Hans J. Grabe,Alexander Teumer,Sandra Van der Auwera,Uwe Völker,Steven P. Hamilton,Patrik K. E. Magnusson,Alexander Viktorin,Divya Mehta,Niamh Mullins,Niamh Mullins,Mark Adams,Gerome Breen,Andrew M. McIntosh,Cathryn M. Lewis,David M. Hougaard,David M. Hougaard,Merete Nordentoft,Merete Nordentoft,Merete Nordentoft,Ole Mors,Ole Mors,Preben Bo Mortensen,Thomas Werge,Thomas Werge,Thomas Werge,Thomas Damm Als,Thomas Damm Als,Anders D. Børglum,Anders D. Børglum,Tracey L. Petryshen,Jordan W. Smoller,Jordan W. Smoller,Jill M. Goldstein +177 more
TL;DR: In the largest genome-wide GxS analysis of mood and psychotic disorders to date, there was substantial genetic overlap between the sexes, but significant sexdependent effects were enriched for genes related to neuronal development, immune and vascular functions across and within SCZ, BIP, and MDD.
Journal Article
Modulation of thermal pain perception by stress and sweet taste in women with bulimia nervosa.
TL;DR: The observed marked modulation of pain threshold by experimental stress suggests that stress-induced analgesia is unlikely to account for baseline pain insensitivity in women with bulimia nervosa.
Journal ArticleDOI
Highly polygenic architecture of antidepressant treatment response: Comparative analysis of SSRI and NRI treatment in an animal model of depression
Karim Malki,Maria Grazia Tosto,Maria Grazia Tosto,Héctor Mouriño‐Talín,Sabela Rodríguez‐Lorenzo,Oliver Pain,Oliver Pain,Irfan Jumhaboy,Tina Liu,Panos Parpas,Stuart Newman,Artem Malykh,Lucia Carboni,Rudolf Uher,Rudolf Uher,Peter McGuffin,Leonard C. Schalkwyk,Kevin Bryson,Mark Herbster +18 more
TL;DR: Methods that can automatically learn to detect patterns of statistical regularity from a sparsely distributed signal across hippocampal transcriptome measurements in a large‐scale animal pharmacogenomic study indicate that the molecular signature of AD treatment may include a much broader range of genomic markers than previously hypothesized.
Journal ArticleDOI
Protocol for a scoping review to support development of a CONSORT extension for randomised controlled trials using cohorts and routinely collected health data
Linda Kwakkenbos,Mahrukh Imran,Kimberly A McCord,Margaret Sampson,Ole Fröbert,Chris Gale,Lars G. Hemkens,Sinead Langan,David Moher,Clare Relton,Merrick Zwarenstein,Eric I Benchimol,Isabelle Boutron,Marion K Campbell,David Erlinge,Sena Jawad,Philippe Ravaud,Danielle B. Rice,Maureen Sauve,Tjeerd van Staa,Lehana Thabane,Rudolf Uher,Helena M. Verkooijen,Edmund Juszczak,Brett D. Thombs +24 more
TL;DR: A scoping review will be conducted to identify potential modifications or clarifications of existing reporting guideline items, as well as additional items needed for reporting RCTs using cohorts and routinely collected health data to help guide the development of the CONSORT extension statement.