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Sally Kornbluth

Researcher at Duke University

Publications -  127
Citations -  12776

Sally Kornbluth is an academic researcher from Duke University. The author has contributed to research in topics: Apoptosis & Xenopus. The author has an hindex of 57, co-authored 127 publications receiving 12234 citations. Previous affiliations of Sally Kornbluth include University of California, San Diego & Rockefeller University.

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Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

Lorenzo Galluzzi, +103 more
TL;DR: A nonexhaustive comparison of methods to detect cell death with apoptotic or nonapoptotic morphologies, their advantages and pitfalls is provided and the importance of performing multiple, methodologically unrelated assays to quantify dying and dead cells is emphasized.
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Cellular Mechanisms Controlling Caspase Activation and Function

TL;DR: There is emerging literature to suggest that caspases can participate in a variety of cellular processes unrelated to apoptoticcell death, and it is likely that continued examination of these processes will reveal new mechanisms of caspase regulation with implications well beyond control of apoptotic cell death.
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Caspases and Kinases in a Death Grip

TL;DR: How the balance between cell survival and cell death can be shifted through crosstalk between these two enzyme families is discussed.
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Apoptosis Induction by Caspase-8 Is Amplified through the Mitochondrial Release of Cytochrome c

TL;DR: Caspase-8 promoted cytochrome c release indirectly, by cleaving at least one cytosolic substrate, potentially explaining why CD95-induced apoptosis can often evade inhibition by Bcl-2.
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Regulatory roles of cyclin dependent kinase phosphorylation in cell cycle control

TL;DR: This work has uncovered new and unexpected potential roles, and prompted re-examination of previously assumed roles, of Cdk phosphorylation, and identified many of the enzymes that act on these sites.